- taxanes
- A class of antitumor agents derived directly or semisynthetically from Taxus brevifolius, the Pacific yew; examples include paclitaxel and docetaxel.
Medical dictionary. 2011.
taxanes
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Taxane — Les taxanes sont une classe très utilisée d agents chimiothérapeutiques[1],[2]. Cette classe comprend le paclitaxel (Taxol) et le docétaxel (Taxotère). À l origine, le paclitaxel (Taxol) a été isolé de l if de l ouest (Taxus brevifolia)[1], un if … Wikipédia en Français
Taxane — The taxanes are diterpenes produced by the plants of the genus Taxus (yews). As their name suggests, they were first derived from natural sources, but some have been synthesized artificially. Taxanes include paclitaxel and docetaxel. Paclitaxel… … Wikipedia
Mitotic inhibitor — The structure of paclitaxel, a widely used mitotic inhibitor. A mitotic inhibitor is a drug that inhibits mitosis, or cell division. These drugs disrupt microtubules, which are structures that pull the cell apart when it divides. Mitotic… … Wikipedia
Discovery and development of tubulin inhibitors — Tubulin inhibitors interfere directly with the tubulin system which is in contrast to those drugs acting on DNA for cancer chemotherapy. Microtubules play an important role in eukaryotic cells. Alpha and beta tubulin, the main components of… … Wikipedia
Chemotherapy — A woman being treated with docetaxel chemotherapy for breast cancer. Cold mittens and wine coolers are placed on her hands and feet to reduce harm to her nails. Chemotherapy (sometimes cancer chemotherapy) is the treatment of cancer with an… … Wikipedia
Paclitaxel — Systematic (IUPAC) name (2α,4α,5β,7β,10β,13α) 4,10 bis(acetyloxy) … Wikipedia
Docetaxel — [1] Docetaxel Systematic (IUPAC) name 1,7β,10β trihydroxy 9 oxo 5β,20 epoxytax 11 ene 2α,4,13α triyl 4 acetate 2 benzoate 13 {(2R,3S) 3 [(tert butoxycarbonyl)amino] 2 hydroxy … Wikipedia
Paclitaxel total synthesis — in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). [Note that the original publications about the total synthesis use the name taxol , which used to be the generic name before it was accepted as… … Wikipedia
Historia de la Quimioterapia — La era de la quimioterapia se inició en la década de 1940 con los primeros usos del gas mostaza y drogas antagónicas al ácido fólico para el tratamiento del cáncer. El desarrollo de medicamentos contra el cáncer se ha convertido en una industria… … Wikipedia Español
History of cancer chemotherapy — The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs. Cancer drug development has exploded since then into a multi billion dollar industry. The targeted therapy revolution has… … Wikipedia
