synaptosome

synaptosome
Membrane-bound sac containing synaptic vesicles that breaks away from axon terminals when brain tissue is homogenized under controlled conditions; such particles can be separated from other subcellular particles by differential and density gradient centrifugation. [synapse + G. soma, body]

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syn·ap·to·some sə-'nap-tə-.sōm n a nerve ending that is isolated from homogenized nerve tissue (as of the brain)
syn·ap·to·som·al -.nap-tə-'sō-məl adj

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syn·ap·to·some (sĭ-napґto-sōm″) any of the membrane-bound sacs that break away from axon terminals at a synapse after brain tissue has been homogenized in sugar solution; it contains synaptic vessels and mitochondria.

Medical dictionary. 2011.

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Look at other dictionaries:

  • synaptosome — [si nap′tə sōm΄] n. 〚see SYNAPSIS & SOME3〛 a tiny sac of special cellular materials found at a synapse * * * syn·ap·to·some (sĭ năpʹtə sōm ) n. A saclike structure formed by nerve endings at a synapse that remains intact after homog …   Universalium

  • synaptosome — [si nap′tə sōm΄] n. [see SYNAPSIS & SOME3] a tiny sac of special cellular materials found at a synapse …   English World dictionary

  • Synaptosome — A synaptosome is an isolated synapse of a neuron. Synaptosomes are obtained after homogenization and fractionation of nerve tissue. The fractionation step involves several centrifugations to separate various organelles from the synaptosomes.… …   Wikipedia

  • synaptosome — noun Etymology: synaptic + o + 3 some Date: 1964 a nerve ending that is isolated from homogenized nerve tissue (as of the brain) • synaptosomal adjective …   New Collegiate Dictionary

  • synaptosome — A subcellular fraction prepared from tissues rich in chemical synapses, used in biochemical studies. Consists mainly of vesicles from presynaptic terminals …   Dictionary of molecular biology

  • synaptosome — noun A structure containing vesicles and mitochondria of a synapse that is obtained when brain tissue is homogenized …   Wiktionary

  • synaptosome — syn·ap·to·some …   English syllables

  • synaptosome — …   Useful english dictionary

  • Cortical synaptosome — Cortical Synatosome is family of drugs, derived from isoquinoline, used to treat depression by preventing reuptake of dopamine by synaptosomes. The maleate was withdrawn from use in 1986 due to side effects including hemolytic anemia and renal… …   Wikipedia

  • SNAP-25 — synaptosome associated protein of 25 kilodaltons …   Medical dictionary

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