Lactate dehydrogenase

Lactate dehydrogenase
An enzyme that catalyzes the conversion of lactate to pyruvate. This is an important step in energy production in cells. Many different types of cells in the body contain this enzyme. Some of the organs relatively rich in lactate dehydrogenase (LDH) are heart, kidney, liver, and muscle. As cells die their LDH is released and finds its way into the blood. Normal LDH levels vary with age, being higher in childhood due to bone growth. Analysis of LDH has not been standardized and normal ranges vary greatly between laboratories. Generally, the upper limit of normal for adults is in the range of 200 units/liter.

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lactate dehydrogenase n any of a group of isoenzymes that catalyze reversibly the conversion of pyruvic acid to lactic acid, are found esp. in the liver, kidneys, striated muscle, and the myocardium, and tend to accumulate in the body when these organs or tissues are diseased or injured called also lactic dehydrogenase

Medical dictionary. 2011.

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  • Lactate dehydrogenase — Identifiers EC number 1.1.1.27 CAS number 9001 60 9 …   Wikipedia

  • lactate dehydrogenase — lactate dehydrogenase. См. лактатдегидрогеназа. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • lactate dehydrogenase — noun : any of a group of isoenzymes that catalyze reversibly the conversion of pyruvic acid to lactic acid, are found especially in the liver, kidneys, striated muscle, and the myocardium, and tend to accumulate in the body when these organs or… …   Useful english dictionary

  • lactate dehydrogenase — LDH. One of a group of enzymes found in the blood and other body tissues and involved in energy production in cells. An increased amount of lactate dehydrogenase in the blood may be a sign of tissue damage and some types of cancer or other… …   English dictionary of cancer terms

  • Lactate dehydrogenase elevating virus — (LDV) is a virus that swiftly multiplies without potentially harming the host. LDV does slightly harm the immune system, causing it to be less efficient. Tests on mice show that LDV is more commonly found in the liver, spleen, lymph nodes, and… …   Wikipedia

  • lactate dehydrogenase — The enzyme that catalyses the formation and removal of lactate according to the equation: pyruvate + NADH = lactate + NAD. The appearance of LDH in the medium is often used as an indication of cell death and the release of cytoplasmic… …   Dictionary of molecular biology

  • lactate dehydrogenase — Biochem. an enzyme that catalyzes the interconversion of pyruvate and lactate, an important step in carbohydrate metabolism: elevated serum levels indicate injury to kidney, skeletal muscle, or heart muscle. Abbr.: LDH * * * …   Universalium

  • lactate dehydrogenase — lac′tate dehy′drogenase n. biochem. an enzyme of carbohydrate metabolism that interchanges lactate and pyruvate: elevated blood levels indicate injury to kidney, heart, or muscles Abbr.: LDH …   From formal English to slang

  • lactate dehydrogenase — /ˌlækteɪt dihaɪˈdrɒdʒəneɪz/ (say .laktayt deehuy drojuhnayz) noun an enzyme existing in multiple forms which catalyses the oxidation of lactate to pyruvic acid used in diagnosis of myocardial infarction …  

  • lactate dehydrogenase — noun Date: 1966 any of a group of isoenzymes that catalyze reversibly the conversion of pyruvic acid to lactic acid called also lactic dehydrogenase …   New Collegiate Dictionary

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