The first sulfonamide used for its chemotherapeutic effect in infections caused by some β-hemolytic streptococci, meningococci, gonococci, Clostridium welchii, and in certain infections of the urinary tract, especially those due to Escherichia coli and Proteus vulgaris; less effective than sulfapyridine in the treatment of pneumococcic, staphylococcic, and Klebsiella pneumoniae infections. Toxic manifestations include acidosis, cyanosis, hemolytic anemia, and agranulocytosis.

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sul·fa·nil·amide or chiefly Brit sul·pha·nil·amide .səl-fə-'nil-ə-.mīd, -məd n a crystalline sulfonamide C6H8N2O3S that is the amide of sulfanilic acid and the parent compound of most of the sulfa drugs

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sul·fa·nil·a·mide (sul″fə-nilґə-mīd) a potent antibacterial compound, the first of the sulfonamides discovered. Formerly used in the treatment of various infections, it has been replaced as a systemic agent by more effective and less toxic derivatives, and by antibiotics; it is still used vaginally in the treatment of vulvovaginal candidiasis.

Medical dictionary. 2011.

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  • Sulfanilamide — Général Nom IUPAC 4 aminobenzenesulfonamide Synonymes …   Wikipédia en Français

  • Sulfanilamide — Systematic (IUPAC) name 4 aminobenzenesulfonamide Clinical data AHFS/ …   Wikipedia

  • sulfanilamide — ● sulfanilamide nom masculin Dénomination courante du para aminobenzène sulfonamide, qui est l amide de l acide sulfanilique et qui a été le premier sulfamide antibactérien. sulfanilamide [sulfanilamid] n. m. ou f. ÉTYM. Après 1937; angl.… …   Encyclopédie Universelle

  • sulfanilamide — sulfanilamide. См. сульфаниламид. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • sulfanilamide — [sul΄fənil′ə mīd΄, sul΄fə nil′əmid] n. [< SULFANILIC ACID + AMIDE] a white, crystalline compound, C6H8N2O2S, formerly used in treating gonorrhea, streptococcal infections, etc.: a synthetic coal tar product …   English World dictionary

  • sulfanilamide — sulfanilamidas statusas T sritis chemija apibrėžtis Antibiotikas. formulė H₂NC₆H₄SO₂NH₂ atitikmenys: angl. sulfanilamide rus. стрептоцид; сульфаниламид ryšiai: sinonimas – streptocidas sinonimas – 4 aminobenzensulfamidas …   Chemijos terminų aiškinamasis žodynas

  • sulfanilamide — noun Etymology: sulfanilic acid (C6H7NO3S, from International Scientific Vocabulary sulf + aniline + ic) + amide Date: 1937 a crystalline sulfonamide C6H8N2O2S that is the parent compound of most of the sulfa drugs …   New Collegiate Dictionary

  • sulfanilamide — /sul feuh nil euh muyd , mid/, n. Pharm. a white, crystalline amide of sulfanilic acid, C6H8N2O2S, formerly used in the treatment of bacterial infections: replaced by its derivatives and by antibiotics. [1935 40; SULFANIL(IC ACID) + AMIDE] * * * …   Universalium

  • sulfanilamide — noun Any of a class of amino substituted aromatic sulfonamides that are used as antifungal antibiotics; but especially the parent compound 4 aminobenzenesulfonamide …   Wiktionary

  • sulfanilamide — n. white crystalline amide of sulfanilic acid that was formerly used to treat bacterial infections …   English contemporary dictionary

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