streptomycin

streptomycin
An antibiotic agent obtained from Streptomyces griseus that is active against the tubercle bacillus and a large number of Gram-positive and Gram-negative bacteria; also used in the form of dihydrostreptomycin (aldehyde of s. reduced to CH2OH). It is a glucoside and contains streptidine and streptobiosamine linked by an oxygen bridge between C-4 of the inositol residue and C-1 of the streptose residue; s. B has a mannose residue attached to the glucosamine and is a natural product, with less activity than s. A. It is used virtually exclusively in the treatment of tuberculosis; toxicity includes eighth cranial nerve damage leading to deafness and/or vestibular dysfunction. SYN: s. A.

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strep·to·my·cin -'mīs-ən n an antibiotic organic base C21H39N7O12 that is produced by a soil actinomycete of the genus Streptomyces (S. griseus), is active against bacteria, and is used esp. in the treatment of infections (as tuberculosis) by gram-negative bacteria

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n.
an aminoglycosides antibiotic, derived from the bacterium Streptomyces griseus, that is used in combination with other drugs for treating tuberculosis and brucellosis. It is administered by intramuscular injection; side-effects causing ear and kidney damage may develop in some patients.

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strep·to·my·cin (strep″to-miґsin) the first of the aminoglycoside antibiotics to be isolated, derived from Streptomyces griseus; it is effective against a wide variety of aerobic gram-negative bacilli and some gram-positive bacteria, including mycobacteria. Its use is now limited because of the emergence of resistant strains.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Streptomycin — См. Стрептомицин (Источник: «Словарь терминов микробиологии») …   Словарь микробиологии

  • streptomycin — streptomycin. См. стрептомицин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Streptomycin — vgl. Streptomyzin …   Das Wörterbuch medizinischer Fachausdrücke

  • streptomycin — (n.) antibiotic drug, 1944, from Mod.L. Streptomyces, genus name of the soil bacterium from which the antibiotic was obtained, from Gk. streptos twisted + mycin, element used in forming names of substances obtained from fungi, from Latinized form …   Etymology dictionary

  • streptomycin — ► NOUN Medicine ▪ an antibiotic used against tuberculosis. ORIGIN from Greek streptos twisted + muk s fungus …   English terms dictionary

  • streptomycin — ☆ streptomycin [strep΄təmī′sin ] n. [< STREPTOMYCES + IN1] an antibiotic, C21H39N7O12, obtained from a soil bacterium ( Streptomyces griseus) and used in treating various bacterial diseases, as tuberculosis …   English World dictionary

  • Streptomycin — drugbox IUPAC name = 5 (2,4 diguanidino 3,5,6 trihydroxy cyclohexoxy) 4 [4,5 dihydroxy 6 (hydroxymethyl) 3 methylamino tetrahydropyran 2 yl] oxy 3 hydroxy 2 methyl tetrahydrofuran 3 carbaldehyde CAS number = 57 92 1 ATC prefix = A07 ATC suffix =… …   Wikipedia

  • Streptomycin — Strukturformel Allgemeines Freiname Streptomycin Andere Namen …   Deutsch Wikipedia

  • Streptomycin — Strep|to|my|cin 〈n. 11; unz.; fachsprachl.〉 = Streptomyzin * * * Strep|to|my|cin [↑ Strepto (1) u. ↑ mycin], das; s: Freiname für ein aus Streptomyces griseus Kulturen isolierbares Aminoglykosid Antibiotikum, das heute noch gegen Tuberkulose… …   Universal-Lexikon

  • streptomycin — /strep teuh muy sin/, n. Pharm. an antibiotic, C21H39N7O12, produced by a soil actinomycete, Streptomyces griseus, and used in medicine in the form of its white, water soluble sulfate salt, chiefly in the treatment of tuberculosis. Cf.… …   Universalium

  • streptomycin A — SYN: streptomycin …   Medical dictionary

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