Kikuchi disease

Kikuchi disease
A disorder that typically causes "swollen glands" in the neck (cervical lymphadenopathy) together with fever or flu-like symptoms. Laboratory test abnormalities include elevated erythrocyte sedimentation rate (ESR), and white blood count abnormalities (low neutrophil count and elevated lymphocyte count with atypical lymphocytes in the peripheral blood). Kikuchi disease is fairly common in young people, predominantly young women, in Asia. Also called Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis, this condition was discovered in Japan in 1972 and since then has seen in other areas of the world. The overall picture is suggestive of a virus infection; autoimmune factors may also play a role. However, no infectious agent has yet been identified and autoimmunity remains hypothetical. Diagnosis is based on characteristic pathologic findings on biopsy that differentiate this disease from others such as lymphoma, systemic lupus erythematosus, and infectious lymphadenopathies.

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Kikuchi-Fujimoto disease see under lymphadenitis.

Medical dictionary. 2011.

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  • Kikuchi — Kikuchi, often written 菊池, can refer to:Several places in Japan: * Kikuchi, Kumamoto * Kikuchi River, Kumamoto * Kikuchi District, KumamotoA Japanese surname: * Kan Kikuchi * Kazuhito Kikuchi * Masami Kikuchi * Mika Kikuchi * Naoya Kikuchi *… …   Wikipedia

  • Disease, Kikuchi — A disorder that typically causes swollen glands in the neck (cervical lymphadeniopathy) together with fever or flu like symptoms. Laboratory test abnormalities include elevated erythrocyte sedimentation rate (ESR), and white blood count… …   Medical dictionary

  • Kikuchi-Fujimoto disease — Ki·ku·chi Fu·ji·mo·to disease (ke kooґche foo je moґto) [M. Kikuchi; Y. Fujimoto, Japanese pathologist, 20th century] Kikuchi lymphadenitis …   Medical dictionary

  • Kikuchi lymphadenitis (disease) — Ki·ku·chi lymphadenitis (disease) (ke kooґche) [M. Kikuchi, Japanese pathologist, 20th century] see under lymphadenitis …   Medical dictionary

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  • Lymphatic disease — Classification and external resources MeSH D008206 Lymphatic disease is a class of disorders which directly affect the components of the lymphatic system. Examples include Castleman s disease …   Wikipedia

  • Autoimmune disease — Autoimmune diseases Classification and external resources ICD 10 D84.9, M35.9 ICD 9 279.4 …   Wikipedia

  • Histiocytic necrotizing lymphadenitis — A disorder, also called Kikuchi disease, that typically causes swollen glands in the neck (cervical lymphadeniopathy) together with fever or flu like symptoms. Laboratory test abnormalities include elevated erythrocyte sedimentation rate (ESR),… …   Medical dictionary

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