An abnormal chromosome with two identical arms due to duplication of one arm and loss of the other arm. (Found in some girls with Turner syndrome and in tumors.)
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A chromosomal aberration that arises as a result of transverse rather than longitudinal division of the centromere during meiosis; two daughter chromosomes are formed, each lacking one chromosome arm but with the other doubled.

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iso·chro·mo·some -'krō-mə-.sōm, -.zōm n a chromosome produced by transverse splitting of the centromere so that both arms are from the same side of the centromere, are of equal length, and possess identical genes

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iso·chro·mo·some (i″so-kroґmə-sōm) [iso- + chromosome] an abnormal chromosome having a median centromere and two identical arms, probably formed by the transverse, rather than the normal longitudinal separation of the centromere of the replicating chromosome. See illustration at aberration.

Medical dictionary. 2011.

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  • Isochromosome — An isochromosome is a chromosome that has lost one of its arms and replaced it with an exact copy of the other arm[1]. This is sometimes seen in some females with Turner syndrome or in tumor cells. This may also cause an isochromosome to have two …   Wikipedia

  • isochromosome — izochromosoma statusas T sritis augalininkystė apibrėžtis Lygiapetė chromosoma su tapačiais genais pečiuose. atitikmenys: angl. isochromosome rus. изохромосома …   Žemės ūkio augalų selekcijos ir sėklininkystės terminų žodynas

  • isochromosome — A chromosome produced following an error in meiosis, in which the two arms are mirror images of each other. The presence of an isochromosome results in the duplication of all genes present on the originating chromosome arm …   Glossary of Biotechnology

  • isochromosome — | ̷ ̷ ̷ ̷+ noun : a chromosome with identical arms believed to be derived from a telocentric chromosome by fusion of two daughter chromosomes * * * isochromosome see iso …   Useful english dictionary

  • isochromosome — noun Date: 1939 a chromosome produced by transverse splitting of the centromere so that both arms are derived from the dyad on one side of the centromere of the parental chromosome and each arm has identical genes arranged in the same order… …   New Collegiate Dictionary

  • isochromosome — adj. [Gr. isos, equal; chromos, color; soma, body] Monocentric or dicentric chromosome with equal and genetically identical arms which are mirror images …   Dictionary of invertebrate zoology

  • isochromosome — noun An abnormal chromosome in which one arm has been lost and replaced with an exact copy of the other arm …   Wiktionary

  • isochromosome — iso·chromosome …   English syllables

  • intermediate; intermittent; internal; internal medicine; intervention; intestine; involvement of a single lymph node [Ann Arbor staging system for Hodgkin disease]; iodine; ionic current; ionic strength; iris; ischemia; isochromosome; isoleucine; isotope; isotropic; nuclear spin quantum number; regi — electric current; incisor [deciduous]; insoluble; isochromosome; optically inactive …   Medical dictionary

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