A place or location or locus. SYN: situs. [L. situs]
- acceptor s. the ribosomal binding s. for the aminoacyl-tRNA during protein synthesis.
- acceptor splicing s. SYN: right splicing junction.
- active s. that portion of an enzyme molecule at which the actual reaction proceeds; considered to consist of one or more residues or atoms in a spatial arrangement that permits interaction with the substrate to effect the reaction of the latter.
- allosteric s. postulated as the place on an enzyme, other than the active s., where a compound, which may be the ultimate product of the biosynthetic pathway involving the enzyme, may bind and influence the activity of the enzyme by changing the enzyme's conformation; the influence of CTP on aspartate carbamoyltransferase activity exemplifies the concept of an allosteric s. on an allosteric protein.
- antibody-combining s. SYN: paratope.
- antigen-binding s. SYN: paratope.
- cleavage s. SYN: restriction s..
- fragile s. [MIM*136540, MIM*136670] a nonstaining gap at a specific point on a chromosome, usually involving both chromatids, always at the same point on chromosomes of different cells from an individual or kindred; it results in in vitro production of acentric fragments, deleted chromosomes, or other chromosome anomalies; inherited as a dominant chromosome marker.
- immunologically privileged sites sites where allografts are not readily rejected or tumors escape immune surveillance probably because these particular areas have poor lymphatic drainage and are not readily accessible to effector cells of the immune system.
- ligand-binding s. the s. on a protein's surface that binds a ligand; equivalent to the active s. if the ligand is the substrate of an enzyme.
- privileged s. an anatomic area lacking lymphatic drainage, such as the brain, cornea, and hamster cheek pouch, in which heterologous tumors may grow because the host does not become sensitized.
- receptor s. point of attachment for viruses, hormones, or other activators to cell membranes.
- replication s. the in vivo s. on DNA of DNA replication.
- restriction s. a s. in nucleic acid in which the bordering bases are of such a type as to leave them vulnerable to the cleaving action of an endonuclease. SYN: cleavage s..
- sequence-tagged sites (STSs) short stretches of DNA sequences that can be detected by use of the polymerase chain reaction.
- switching s. the break point in a DNA sequence at which a gene segment unites with another gene segment, as in the production of the immunoglobulins.

* * *

site 'sīt n the place, scene, or point of something <the \site of inflammation> see active site

* * *

(sīt) a place, position, or locus.

Medical dictionary. 2011.


Look at other dictionaries:

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  • Site — Site, n. [L. situs, fr. sinere, situm, to let, p. p. situs placed, lying, situate: cf. F. site. Cf. {Position}.] 1. The place where anything is fixed; situation; local position; as, the site of a city or of a house. Chaucer. [1913 Webster] 2. A… …   The Collaborative International Dictionary of English

  • site — site. См. сайт. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Site — Cette page d’homonymie répertorie les différents sujets et articles partageant un même nom. Sur les autres projets Wikimedia : « Site », sur le Wiktionnaire (dictionnaire universel) Géographie En géographie, il ne faut pas… …   Wikipédia en Français

  • Site — A site is the location of an event, structure, object, or other thing, whether actual, virtual, abandoned (eg. an archaeological site), extant, or planned.*For a building site, see construction. *For a site on the World Wide Web, see website.In… …   Wikipedia

  • Site W — Karte der einzelnen Bereiche auf der Hanford Site Straßenschild der Hanford Site Hanford Site ist der Name eines US amerikanischen Nuklearkomplexes am Columbia …   Deutsch Wikipedia

  • Site AP — Un site AP est un emplacement de l ADN où la base (normalement attachée) est manquante.En l absence de réparation, il peuvent mener à une rupture simple brin. Lors de la réplication, ils mènent très souvent à une mutation. Un site AP (site… …   Wikipédia en Français

  • site — I. noun Etymology: Middle English, place, position, from Anglo French or Latin; Anglo French sit, site, from Latin situs, from sinere to leave, allow Date: 14th century 1. a. the spatial location of an actual or planned structure or set of… …   New Collegiate Dictionary

  • site — /suyt/, n., v., sited, siting. n. 1. the position or location of a town, building, etc., esp. as to its environment: the site of our summer cabin. 2. the area or exact plot of ground on which anything is, has been, or is to be located: the site… …   Universalium

  • Site — Sculpture in the Environment, más conocido por su acrónimo SITE, es un estudio de arquitectura neoyorkino fundado en 1970 por James Wines y Alison Sky.[1] SITE saltó a la fama en 1975 por una serie de 7 centros comerciales encargados por la… …   Wikipedia Español

  • site — 1. noun /saɪt/ a) The place where anything is fixed; situation; local position; as, the site of a city or of a house. A more full and exact description of the Countrie, and Narration of the nature, site, and commodities, together with a true… …   Wiktionary

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