simvastatin

A potent HMG-CoA reductase (the rate-limiting enzyme for cholesterol biosynthesis) inhibitor. Used for the treatment of hyperlipidemia; similar to lovastatin.

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sim·va·stat·in 'sim-və-.stat-ən, .sim-və-'stat- n a semisynthetic lipid-lowering drug C₂₅H₃₈O₅ derived from a compound produced by a mold of the genus Aspergillus (A. terreus) and administered orally to lower a high cholesterol level in the blood by inhibiting the action of an enzyme catalyzing the synthesis of cholesterol see vytorin, ZOCOR

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n.

a drug used to reduce abnormally high levels of cholesterol in the blood (see statin). Its actions and side-effects are similar to those of atorvastatin. Trade name: Zocor.

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sim·va·stat·in (simґvə-stat″in) [USP] an antihyperlipidemic agent that is an HMG-CoA reductase inhibitor, used to lower blood lipid levels in the treatment of hypercholesterolemia and other forms of dyslipidemia and to reduce the risk of morbidity and mortality associated with atherosclerosis and coronary heart disease; administered orally.