selegiline

selegiline
A monoamine oxidase enzyme inhibitor; inhibits only the type B isozyme so that consuming tyramine-containing foods or beverages is less likely to induce hypertensive crisis in persons treated with s. than in persons treated with nonselective monoamine oxidase inhibitors. The drug is used in the treatment of Parkinson disease. SYN: deprenyl.

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se·leg·i·line si-'lej-ə-.lēn n the levorotatory form of the monoamine oxidase inhibitor deprenyl that is administered in the form of its hydrochloride C13H17N·HCl as an adjuvant to therapy using the combination of L-dopa and carbidopa in the treatment of Parkinson's disease and is sometimes used alone to treat endogenous depression or to treat dementia associated with Alzheimer's disease

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n.
a selective MAO inhibitor used in the treatment of parkinsonism. Administered by mouth, selegiline is thought to retard the breakdown of dopamine. Possible side-effects include faintness on standing up, nausea, involuntary movements, and confusion. Trade names: Eldepryl, Zelapar.

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se·le·gil·ine (sə-lejґə-lēn) an inhibitor of monoamine oxidase type B; used in the treatment of major depressive disorder, administered transdermally.

Medical dictionary. 2011.

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