quinacrine hydrochloride

quinacrine hydrochloride
An acridine derivative, used as an antimalarial that destroys the trophozoites of Plasmodium vivax and P. falciparum, but does not affect the gametocytes, sporozoites, or exoerythrocytic stage of parasites; also used as an anthelmintic. As a dihydrochloride, it is used as a stain in cytogenetics to demonstrate Y chromatin by fluorescent microscopy. Q. intercalates with DNA and also uncouples oxidation and photophosphorylation. SYN: atabrine hydrochloride, mepacrine hydrochloride.

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quin·a·crine hy·dro·chlo·ride (kwinґə-krin) an antimalarial, antiprotozoal, and anthelmintic, used especially for suppressive therapy of malaria and in the treatment of giardiasis and tapeworm infestations, administered orally. Called also chinacrine hydrochloride and mepacrine hydrochloride.

Medical dictionary. 2011.

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Look at other dictionaries:

  • quinacrine hydrochloride — [kwin′ə krēn΄] n. 〚 QUIN(INE) + ACR(ID)INE〛 ATABRINE * * * …   Universalium

  • quinacrine hydrochloride — [kwin′ə krēn΄] n. [ QUIN(INE) + ACR(ID)INE] ATABRINE …   English World dictionary

  • quinacrine hydrochloride — noun a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malaria • Syn: ↑quinacrine, ↑mepacrine, ↑Atabrine • Usage Domain: ↑trade name (for: ↑Atabrine) …   Useful english dictionary

  • Quinacrine — Systematic (IUPAC) name (RS) N (6 chloro 2 methoxy acridin 9 yl) N, N diethyl pentane 1,4 diamine Clinical data Trade names …   Wikipedia

  • mepacrine hydrochloride — SYN: quinacrine hydrochloride. * * * mep·a·crine hy·dro·chlo·ride (mepґə krēn) quinacrine hydrochloride …   Medical dictionary

  • atabrine hydrochloride — SYN: quinacrine hydrochloride …   Medical dictionary

  • quin|a|crine hydrochloride — quin|a|crine hydrochloride, or quin|a|crine «KWIHN uh kreen, krihn», noun. a drug used in the treatment of malaria; Atabrine: »Atabrine is the trade name given this drug by the Germans and has been so commonly used that it is employed here. The… …   Useful english dictionary

  • stain — 1. To discolor. 2. To color; to dye. 3. A discoloration. 4. A dye used in histologic and bacteriologic technique. 5. A procedure in which a dye or combination of dyes and reagents is used to color the constituents of cells and tissues. For… …   Medical dictionary

  • antimalarial — noun a medicinal drug used to prevent or treat malaria • Syn: ↑antimalarial drug • Hypernyms: ↑antiprotozoal, ↑antiprotozoal drug • Hyponyms: ↑chloroquine, ↑mefloquine, ↑ …   Useful english dictionary

  • antimalarial drug — noun a medicinal drug used to prevent or treat malaria • Syn: ↑antimalarial • Hypernyms: ↑antiprotozoal, ↑antiprotozoal drug • Hyponyms: ↑chloroquine, ↑mefloquine, ↑ …   Useful english dictionary

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