pyrazinamide

pyrazinamide
First-line antituberculosis drug, particularly active against Mycobacterium tuberculosis in macrophages. Like all antituberculosis drugs, it must be given with other drugs to be effective in active disease. Its major toxicity is hepatic.

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pyr·a·zin·amide .pir-ə-'zin-ə-.mīd, -məd n a tuberculostatic drug C5H5N3O

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n.
a drug administered by mouth, usually in combination with other drugs, to treat tuberculosis. Side-effects may include digestive upsets, joint pains, gout, fever, and rashes, and high doses may cause liver damage. Trade name: Zinamide.

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pyr·a·zin·a·mide (PZA) (pir″ə-zinґə-mīd) [USP] an antibacterial derived from nicotinic acid, used as a tuberculostatic, administered orally.

Medical dictionary. 2011.

Look at other dictionaries:

  • Pyrazinamide — Systematic (IUPAC) name pyrazine 2 carboxamide Clinical data Trade names Rifater …   Wikipedia

  • pyrazinamide — /pir euh zin euh muyd , mid/, n. Pharm. a substance, C5H5N3O, used in the treatment of tuberculosis. [1950 55; pyrazine ( < G Pyrazin, alter. of Pyridin PYRIDINE, by insertion of az AZ ) + AMIDE] * * * …   Universalium

  • pyrazinamide — noun A bacteriostatic drug, pyrazine 2 carboxamide, used to treat tuberculosis …   Wiktionary

  • pyrazinamide — pyr·a·zin·amide …   English syllables

  • pyrazinamide — n. a drug administered by mouth, in combination with other drugs, to treat tuberculosis. Side effects may include digestive upsets, loss of appetite, joint pains, gout, fever, and rashes, and high doses may cause liver damage …   The new mediacal dictionary

  • pyrazinamide — ˌpirəˈzinəˌmīd, mə̇d noun Etymology: pyrazine + amide : a tuberculostatic drug C4H3N2CONH2; pyrazine carboxamide …   Useful english dictionary

  • PZA — • pyrazinamide …   Dictionary of medical acronyms & abbreviations

  • Пиразинамид — (Pyrazinamide) Химическое соединение …   Википедия

  • PZA — PyraZinAmide (Medical » Physiology) PyraZinAmide (Medical » Human Genome) …   Abbreviations dictionary

  • PZA — pyrazinamide * * * pyrazinamide …   Medical dictionary

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