polyamine

polyamine
Class name for substances of the general formula H2N(CH2)nNH2, H2N(CH2)nNH(CH2)nNH2, H2N(CH2)nNH(CH2)nNH(CH2)nNH2, where n = 3, 4, or 5. Many polyamines arise by bacterial action on protein; many are normally occurring body constituents of wide distribution or are essential growth factors for microorganisms. [G. polys, much, many + amine]
- p. oxidase an enzyme of liver peroxisomes that uses molecular oxygen to oxidize spermine to spermidine and spermidine to putrescine, in both cases also producing H2O2 and β-aminopropionaldehyde; a part of the catabolic pathway of polyamines.

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poly·amine 'päl-ē-ə-.mēn, .päl-ē-'am-.ēn n a compound characterized by more than one amino group

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poly·am·ine (pol″e-amґēn) any compound, e.g., spermine and spermidine, containing two or more amine groups joined by a short hydrocarbon chain. Polyamines are low molecular weight cations and are synthesized within cells to provide intermediates for protein synthesis; they are important in cell growth and proliferation, gene expression, and extracellular matrix synthesis.

Medical dictionary. 2011.

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  • polyamine — [ pɔliamin ] n. f. • 1898; de poly et amine ♦ Chim., biol. Substance aliphatique linéaire possédant plusieurs fonctions amine. ● polyamine nom féminin Composé chimique renfermant plusieurs fonctions amine. polyamine n. f. CHIM Corps possédant… …   Encyclopédie Universelle

  • Polyamine — Unter Polyamine werden meist gesättigte, offenkettige oder cyclische organische Verbindungen zusammenfasst, mit endständigen Aminogruppen, unterbrochen von einer wechselnden Anzahl sekundärer Aminogruppen.[1] Polyamine sind je nach Kettenlänge… …   Deutsch Wikipedia

  • Polyamine — [ thumb|spermine] The polyamines are organic compounds having two or more primary amino groups such as putrescine, cadaverine, spermidine, and spermine that are growth factors in both eucaryotic and procaryotic cells. Cyclen is the main… …   Wikipedia

  • Polyamine — Putrescine ou diaminobutane, une polyaamine qui participe à donner aux cadavres en décomposition leur odeur. Les polyamines sont des composés organiques possédant deux ou plusieurs fonctions amine. Parmi les composés répondant à cette définition …   Wikipédia en Français

  • polyamine — “+ noun Etymology: International Scientific Vocabulary poly + amine : a compound characterized by more than one amino group * * * /pol ee euh meen , am in/, n. Chem. a compound containing more than one amino group. [1860 65; POLY + AMINE] * * *… …   Useful english dictionary

  • Polyamine-modulated factor 1 — Polyamine modulated factor 1, also known as PMF1, is a human gene.cite web | title = Entrez Gene: PMF1 polyamine modulated factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=11243| accessdate = ] PBB… …   Wikipedia

  • Polyamine-transporting ATPase — In enzymology, a polyamine transporting ATPase (EC number|3.6.3.31) is an enzyme that catalyzes the chemical reaction:ATP + H2O + polyamineout ightleftharpoons ADP + phosphate + polyamineinThe 3 substrates of this enzyme are ATP, H2O, and… …   Wikipedia

  • Polyamine oxidase — In enzymology, a polyamine oxidase (EC number|1.5.3.11) is an enzyme that catalyzes the chemical reaction:N1 acetylspermine + O2 + H2O ightleftharpoons N1 acetylspermidine + 3 aminopropanal + H2O2The 3 substrates of this enzyme are N1… …   Wikipedia

  • polyamine oxidase — noun Any enzyme that catalyzes the oxidation of a polyamine, but especially of acetylspermine to acetylspermidine and aminopropanal …   Wiktionary

  • polyamine — noun Date: 1861 a compound characterized by more than one amino group …   New Collegiate Dictionary

  • polyamine — Polycations at physiological pH, polyamines can bind and interact with various other molecules within the cell. In particular interact with DNA but also may modulate ion channels and act as growth factors. Spermine has four positive charges,… …   Dictionary of molecular biology

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