Histiocytosis, Hand-Schuller-Christian

Histiocytosis, Hand-Schuller-Christian
A disease in which histiocytes start to multiply and attack the tissues or organs of the patient. The disease usually affects children age 2 to 5, less often older children and adults. The most frequent sites of bony involvement are the flat bones of the skull, ribs, pelvis, and scapula (wing bone). Chronic otitis media due to involvement of the mastoid and the temporal bone is common. Diabetes insipidus affects some patients, mainly children who have systemic disease. Up to 40% of children with it have short stature. Hand-Schuller-Christian disease is a form of Langerhans cell histiocytosis.

Medical dictionary. 2011.

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  • Hand-Schüller-Christian-Syndrom — Klassifikation nach ICD 10 C96.0 Abt Letterer Siwe Krankheit Letterer Siwe Syndrom C96.1 Maligne Histiozytose D76.0 …   Deutsch Wikipedia

  • Hand-Schuller-Christian disease — Hand Schül·ler Chris·tian disease .hand .shü lər kris(h) chən n an inflammatory histiocytosis associated with disturbances in cholesterol metabolism that occurs chiefly in young children and is marked by cystic defects of the skull and by… …   Medical dictionary

  • Hand-Schuller-Christian disease — noun inflammatory histiocytosis associated with disturbance of cholesterol metabolism; occurs chiefly in young children and is characterized by cystic defects of the skull and diabetes insipidus • Syn: ↑Schuller Christian disease • Hypernyms:… …   Useful english dictionary

  • Hand-Schüller-Christian disease — see Langerhans cell histiocytosis [A. Hand (1868–1949), US paediatrician; A. Schüller (1874–1958), Austrian neurologist; H. A. Christian (1876–1951), US physician] …   The new mediacal dictionary

  • Schuller-Christian disease — noun inflammatory histiocytosis associated with disturbance of cholesterol metabolism; occurs chiefly in young children and is characterized by cystic defects of the skull and diabetes insipidus • Syn: ↑Hand Schuller Christian disease • Hypernyms …   Useful english dictionary

  • Histiocytosis — Classification and external resources ICD 10 C96.1, D76.0 ICD 9 …   Wikipedia

  • Histiocytosis X — Klassifikation nach ICD 10 C96.0 Abt Letterer Siwe Krankheit Letterer Siwe Syndrom C96.1 Maligne Histiozytose D76.0 …   Deutsch Wikipedia

  • Histiocytosis — A rare but potentially deadly disorder with similarities to cancer, in which histiocytes start to multiply and attack the person’s own tissues or organs. The result can be tissue damage, pain, development of tumor like lumps called granulomas,… …   Medical dictionary

  • histiocytosis — noun a blood disease characterized by an abnormal multiplication of macrophages • Hypernyms: ↑blood disease, ↑blood disorder • Hyponyms: ↑Hand Schuller Christian disease, ↑Schuller Christian disease …   Useful english dictionary

  • Langerhans cell histiocytosis — Classification and external resources Micrograph showing a Langerhans cell histiocytosis with the characteristic reniform Langerhans cells accompanied by abundant eosinophils. H E stain …   Wikipedia

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