- Movements of drugs within biologic systems, as affected by uptake, distribution, binding, elimination, and biotransformation; particularly the rates of such movements. [pharmaco- + G. kinesis, movement]
* * *phar·ma·co·ki·net·ics -kō-kə-'net-iks, -kō-kī- n pl but sing in constr1) the study of the bodily absorption, distribution, metabolism, and excretion of drugs2) the characteristic interactions of a drug and the body in terms of its absorption, distribution, metabolism, and excretion <evaluated the \pharmacokinetics of a single theophylline dose (Jour. Amer. Med. Assoc.)>phar·ma·co·ki·net·ic -ik adj
* * *n.the study of how drugs are handled within the body, including their absorption, distribution, metabolism, and excretion. It is concerned with such matters as how drug concentration in the body changes with time, how drugs pass across cell membranes, how often they should be given, what the effect of long-term administration may be, how drugs interact with each other, and how individual variations affect all these things.
* * *phar·ma·co·ki·net·ics (fahr″mə-ko-kĭ-netґiks) the activity or fate of drugs in the body over a period of time, including the processes of absorption, distribution, localization in tissues, biotransformation, and excretion.
Medical dictionary. 2011.