paraprotein

paraprotein
1. A monoclonal immunoglobulin of blood plasma, observed electrophoretically as an intense band in γ, β, or α regions, due to an isolated increase in a single immunoglobulin type as a result of a clone of plasma cells arising from the abnormal rapid multiplication of a single cell. The finding of a p. in a patient's serum indicates the presence of a proliferating clone of immunoglobulin-producing cells and may be seen in a variety of malignant, benign, or nonneoplastic diseases. 2. SYN: monoclonal immunoglobulin. [para + protein, fr. G. protos, first]

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para·pro·tein -'prō-.tēn, -'prōt-ē-ən n any of various abnormal serum globulins with unique physical and electrophoretic characteristics

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n.
an abnormal protein of the immunoglobulin series. Paraproteins appear in malignant disease of the spleen, bone marrow, liver, etc. Examples of paraproteins are myeloma globulins, Bence-Jones protein, and macroglobulin.

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para·pro·tein (par″ə-proґtēn) M component.

Medical dictionary. 2011.

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  • Paraprotein — Serum protein electrophoresis showing a paraprotein (peak in the gamma zone) in a patient with multiple myeloma. A paraprotein is an immunoglobulin or immunoglobulin light chain that is produced in excess by the clonal proliferation of plasma… …   Wikipedia

  • Paraprotein — M Gradient in der Elektrophorese bei Multiplen Myelom Bei den Paraproteinen handelt es sich um Eiweißkörper – meist funktionslose Immunglobuline (Antikörper) oder deren einzelne Bestandteile – im Blut oder Urin, die bei der Elektrophorese… …   Deutsch Wikipedia

  • paraprotein — ˌ noun Etymology: para (I) + protein : any of various abnormal serum globulins with unique physical and electrophoretic characteristics * * * paraprotein(æmia see para 1 2 a …   Useful english dictionary

  • paraproteinæmia — paraprotein(æmia see para 1 2 a …   Useful english dictionary

  • paraprotein — noun A protein found in the blood only as a result of disease …   Wiktionary

  • Paraprotein — Pa|ra|pro|te|in [↑ para (5)]: bei bestimmten pathologischen Prozessen (Paraproteinämien) nachweisbare monoklonale Immunglobuline, z. B. Bence Jones u. Amyloid Proteine. * * * Pa|ra|pro|te|in, das; s, e <meist Pl.> [zu ↑para , Para u.… …   Universal-Lexikon

  • Paraprotein — Para|prote|i̱n [↑para... u. ↑Protein] s; s, e (meist Mehrz.): entartete Eiweißkörper im Blut (unwirksame Antikörperglobuline), die sich bei bestimmten Blutkrankheiten bilden …   Das Wörterbuch medizinischer Fachausdrücke

  • Paraprotein — Pa|ra|pro|te|in das; s, e (meist Plur.) <zu ↑para... u. ↑Protein> entarteter Eiweißkörper im Blut, der sich bei bestimmten Blutkrankheiten bildet (Med.) …   Das große Fremdwörterbuch

  • paraprotein — para·protein …   English syllables

  • paraprotein — n. an abnormal protein of the immunoglobulin series. Paraproteins appear in malignant disease of the spleen, bone marrow, liver, etc. Examples of paraproteins are myeloma globulins, Bence Jones protein, and macroglobulin …   The new mediacal dictionary

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