pachydermoperiostosis

A syndrome of clubbing of the digits, periosteal new bone formation, especially over the distal ends of the long bones (idiopathic hypertrophic osteoarthropathy), and coarsening of the facial features with thickening, furrowing, and oiliness of the skin of the face and forehead (cutis verticis gyrata); there is seborrheic hyperplasia with open sebaceous pores filled with plugs of sebum; often of autosomal dominant inheritance, usually more severe in males. SYN: acropachyderma. [pachy- + G. derma, skin, + periostosis]

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pachy·der·mo·peri·os·to·sis (pak″e-dur″mo-per″e-os-toґsis) [pachy- + dermo- + periostosis] a rare syndrome characterized by pachyderma with deep folds and furrows on the forehead, cheeks, and scalp (cutis verticis gyrata), as well as seborrhea, hyperhidrosis, periostosis of long bones, digital clubbing, and spadelike enlargement of the hands and feet. It is more prevalent in males and usually first appears during adolescence. Some forms are hereditary and others are secondary to cardiopulmonary diseases or malignancies. Called also idiopathic or primary hypertrophic osteoarthropathy and Touraine-Solente-Golй syndrome.