Guillain-Barre syndrome

Guillain-Barre syndrome
This disorder is characterized by progressive symmetrical paralysis and loss of reflexes, usually beginning in the legs, with in most cases nearly complete or complete recovery. The Guillain-Barre syndrome is not associated with fever (although the patient may have fever for other reasons). The paralysis characteristically involves more than one limb, most commonly the legs. The paralysis is progressive and usually ascending. There is areflexia (loss of reflexes) or hyporeflexia (diminution of reflexes) in the legs and arms. Other conditions that may mimic the Guillain- Barre syndrome need to be ruled out. Usually occurring after a respiratory infection, it is caused by a misdirected immune response that results in the direct destruction of the myelin sheath surrounding the peripheral nerves, or of the axon of the nerve itself. The syndrome sometimes follows other triggering events, including vaccinations. Among the vaccines reportedly associated with Guillain-Barre syndrome are the 1976-1977 swine flu vaccine, oral poliovirus vaccine, and tetanus toxoid. Aside from vaccinations, infection with the bacteria Campylobacter jejuni and viral infections can trigger Guillain-Barre syndrome. Other conditions that may mimic the Guillain-Barre syndrome need to be ruled out before diagnosis is made. Treatment is by plasmapheresis or intravenous gamma globulin (IGG). See also demyelination, Landry’s paralysis.

* * *

Guil·lain-Bar·ré syndrome .gē-.lan-.bä-'rā-, .gē-yan- n a polyneuritis of unknown cause characterized esp. by muscle weakness and paralysis called also Landry's paralysis
Guillain gē-yan Georges Charles (1876-1961), and
Barré bä-rā Jean Alexander (1880-1967)
French neurologists. Guillain published several significant neurological studies concerning the brain and the spinal column. An authority on the spinal column in particular, he made studies of the cerebrospinal fluid and the marrow of the spinal cord. Guillain and Barré published their description of the Guillain-Barré syndrome in 1916.

* * *

a disease of the peripheral nerves in which there is numbness and weakness in the limbs. It usually develops 10-20 days after a respiratory or gastrointestinal infection (commonly with Campylobacter) that provokes an allergic response in the peripheral nerves. Involvement of the respiratory muscles may require mechanical ventilation. Recovery is usually excellent although often prolonged. Treatment with immunoglobulins (intravenous) or with plasma exchange may speed recovery and reduce long-term disability. See polyradiculitis.
G. Guillain (1876-1961) and A. Barré (1880-1967), French neurologists

Medical dictionary. 2011.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Guillain–Barré syndrome — Guillain Barré syndrome Classification and external resources ICD 10 G61.0 ICD 9 357.0 …   Wikipedia

  • Guillain-Barré syndrome — [gē lan΄bä rā′, gēlan′bä rā′] n. [after G. Guillain & J. Barré, 20th c. Fr neurologists] an acute neurological disorder of unknown cause, involving partial paralysis of several muscle groups and occurring rarely after certain viral infections and …   English World dictionary

  • Guillain-Barré syndrome — Infobox Disease Name = Guillain Barré syndrome Caption = DiseasesDB = 5465 ICD10 = ICD10|G|61|0|g|60 ICD9 = ICD9|357.0 ICDO = OMIM = 139393 MedlinePlus = 000684 eMedicineSubj = emerg eMedicineTopic = 222 eMedicine mult = eMedicine2|neuro|7… …   Wikipedia

  • Guillain-Barre syndrome — noun a form of peripheral polyneuritis characterized by pain and weakness and sometimes paralysis of the limbs; cause is unknown • Syn: ↑infectious polyneuritis, ↑Landry s paralysis • Hypernyms: ↑polyneuritis, ↑multiple neuritis * * *… …   Useful english dictionary

  • Guillain–Barré syndrome — [ˌgɪjaGuillain–Barré syndrome bareɪ] noun Medicine an acute disorder of the peripheral nerves causing weakness and often paralysis of the limbs. Origin 1916: named after the French physicians G. Guillain and J. Barré, who described the syndrome …   English new terms dictionary

  • Guillain-Barré syndrome (GBS) and hallucinations —    GBS is known under more than 20 names, including Guillain Barré Strohl syndrome, Landry Guillain Barré syndrome, Landry s paralysis,    Landry s ascending paralysis, Landry s syndrome, Kussmaul Landry syndrome, Landry Kussmaul syndrome, acute… …   Dictionary of Hallucinations

  • Guillain-Barré syndrome — noun Etymology: Georges Guillain died 1961 French physician and Jean A. Barré died 1967 French neurologist Date: 1939 a polyneuritis of unknown cause characterized especially by muscle weakness and paralysis …   New Collegiate Dictionary

  • Guillain-Barré syndrome — /gee yan beuh ray /, Pathol. an uncommon, usually self limited form of polyneuritis, occurring after a viral illness or immunization and manifested by loss of muscle strength, loss of or altered sensation and sometimes paralysis. [after French… …   Universalium

  • Guillain-Barré syndrome — postinfective polyneuropathy a disease of the peripheral nerves in which there is numbness and weakness in the limbs. It usually develops 1–28 days after a respiratory or gastrointestinal infection (commonly with Campylobacter) that provokes an… …   The new mediacal dictionary

  • Guillain-Barré syndrome — /gilæn ˈbareɪ sɪndroʊm/ (say geelan bahray sindrohm) noun Medicine a disorder in which the body s immune system attacks part of the peripheral nervous system, causing weakness or tingling sensations in the arms, legs, and upper body which can be… …  

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”