That part of the healing process in which rough, pink tissue containing new connective tissue and capillaries forms around the edges of a wound. Granulation of a wound is normal and desirable.
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1. Formation into grains or granules; the state of being granular. 2. A granular mass in or on the surface of any organ or membrane; or one of the individual granules forming the mass. 3. The formation of minute, rounded, fleshy connective tissue projections on the surface of a wound, ulcer, or inflamed tissue surface in the process of healing; one of the fleshy granules composing this surface. SEE ALSO: g. tissue. 4. In pharmacy, the formation of crystals by constant agitation of a supersaturated solution of a salt; product used in the manufacture of tablets for oral use. SYN: granulatio. [L. granulatio]
- arachnoid granulations [TA] tufted prolongations of pia-arachnoid, composed of numerous arachnoid villi that penetrate dural venous sinuses and effect transfer of cerebrospinal fluid to the venous system. At advanced age these are more numerous and tend to calcify. SYN: arachnoidal granulations [TA], granulationes arachnoideae [TA], pacchionian bodies, pacchionian corpuscles, pacchionian glands, pacchionian granulations.
- arachnoidal granulations [TA] SYN: arachnoid granulations.
- pacchionian granulations SYN: arachnoid granulations.

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gran·u·la·tion .gran-yə-'lā-shən n
1) the act or process of granulating: the condition of being granulated
2 a) one of the small elevations of a granulated surface: (1) a minute mass of tissue projecting from the surface of an organ (as on the eyelids in trachoma) (2) one of the minute red granules made up of loops of newly formed capillaries that form on a raw surface (as of a wound) and that with fibroblasts are the active agents in the process of healing see GRANULATION TISSUE
b) the act or process of forming such elevations or granules

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the formation of a multicellular mass of tissue (granulation tissue) in response to an injury: this is an essential part of the healing process. Granulation tissue contains many new blood vessels and, in its later stages, large numbers of fibroblasts. The response is most frequently seen in healing open wounds and in the bases of ulcers.

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gran·u·la·tion (gran″u-laґshən) [L. granulatio] 1. the process of forming granulation tissue. 2. the process of forming cytoplasmic granules. 3. granule (def. 1). 4. any granular material on the surface of a tissue, membrane, or organ. the rendering of hard or metallic substances into granules or grains.

Medical dictionary. 2011.

Look at other dictionaries:

  • granulation — [ granylasjɔ̃ ] n. f. • 1651; de granuler 1 ♦ Techn. Formation d une substance en petits grains (par réduction, agglomération). Granulation d un métal par fusion et passage au crible. Métall. Opération consistant à mettre en contact un alliage en …   Encyclopédie Universelle

  • Granulation — Gran u*la tion, n. [Cf. F. granulation.] 1. The act or process of forming or crystallizing into grains; as, the granulation of powder and sugar. [1913 Webster] 2. The state of being granulated. [1913 Webster] 3. (Med.) (a) One of the small, red,… …   The Collaborative International Dictionary of English

  • Granulation — can refer to:*Granulation tissue, a product of healing in major wounds; *Granular synthesis, a sound synthesis method; *Solar granulation, a sign of turbulent convection on the Sun; or *a process used by goldsmiths or silversmiths to decorate… …   Wikipedia

  • Granulation — (lat., »Körnung, Körnchenbildung«), Bildung der Fleischwärzchen auf heilenden Wunden und Geschwüren, durch die deren Heilung bewirkt wird. Die Fleischwärzchen sind rötliche, stecknadelkopfgroße Körnchen, die aus zahlreichen zarten und… …   Meyers Großes Konversations-Lexikon

  • Granulation — (v. lat., Med.), 1) die bei Eiterung sich bildenden Fleischwärzchen, s. Eiter; 2) Pachioni sche Granulationen, kleine Knötchen in den Hirnhäuten; 3) G. (Granulardegeneration) der Nieren, so v.w. Bright sche Krankheit, s.d.; 4) G. der Gebärmutter… …   Pierer's Universal-Lexikon

  • Granulation — (lat.), Körnung, gekörntes Aussehen; in der Medizin die Bildung körniger Fleischwärzchen (aus Haargefäßen und Bindegewebe) auf Wunden und Geschwüren, wodurch deren Heilung bewirkt wird; bei übermäßiger Wucherung, entsteht das sog. wilde Fleisch,… …   Kleines Konversations-Lexikon

  • Granulation — Granulation, lat. dtsch., Pulverung; in der Medicin der Krankheitsprozeß, in Folge dessen eine mit körnigen Erhabenheiten bedeckte Fläche erscheint; in der Pharmacie die Zerkleinerung eines festen Körpers; die Behandlung leicht schmelzbarer… …   Herders Conversations-Lexikon

  • granulation — 1610s, from L.L. granulum (see GRANULAR (Cf. granular)) + ATION (Cf. ation) …   Etymology dictionary

  • granulation — [gran΄yə lā′shən] n. 1. formation into granules or grains 2. Med. a) the formation of a small mass of tiny red granules of newly formed capillaries, as on the surface of a wound that is healing b) the mass itself …   English World dictionary

  • Granulation — Der Begriff Granulation, allgemein etwa Körnung bedeutend, wird in verschiedenen Fachbereichen verwendet: Granulation (Astronomie), insbesondere die körnige Struktur der Sonnenoberfläche Granulation (Goldschmiedekunst) Granulation (Informatik)… …   Deutsch Wikipedia

  • granulation — /gran yeuh lay sheuhn/, n. 1. the act or process of granulating. 2. a granulated condition. 3. any of the grains of a granulated surface. 4. Pathol. a. the formation of granulation tissue, esp. in healing. b. See granulation tissue. 5. Astron.… …   Universalium

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