- mutant
- 1. A phenotype in which a mutation is manifested. 2. A gene that is rare and usually harmful, in contrast to a wild-type gene, not necessarily generated recently.- active m. a m. with overt phenotypic expression.- auxotrophic m. m. with a nutritional requirement not present in the wild-type organism. SYN: defective organism, deficiency m..- cold-sensitive m. a m. that is defective at low temperature but functional at normal temperature. Cf.:temperature-sensitive m..- conditionally lethal m. a viral m. that can replicate under some (permissive) conditions but not under other (restrictive or nonpermissive) conditions, the parent (wild-type) strain being able to replicate under both conditions. See suppressor-sensitive m., temperature-sensitive m.. SYN: conditional-lethal m..- deficiency m. SYN: auxotrophic m..- inactive m. a m. that is not phenotypically manifest. SYN: silent m..- petite m. a m. with a mutation that caused the microorganism to grow very slowly or to form small colonies. [Fr. small]- quick-stop m. a bacterial m. that ceases replication immediately when the temperature reaches a certain level. Cf.:temperature-sensitive m..- silent m. SYN: inactive m..- suppressor-sensitive m. a conditionally lethal, host range, bacteriophage m. that produces nonsense codons and can replicate only in a host bacterium able to translate the nonsense codon; the mutation's effects are lethal ( i.e., prevent replication of the virus) in a bacterium without such a suppressor mechanism.- temperature-sensitive m. a viral m. that is able to replicate at one portion of a temperature range but not at another, the parent (wild-type) strain being able to replicate over the whole temperature range; usually a product is not made at the elevated temperature. Cf.:cold-sensitive m., quick-stop m..- uninducible m. a m. that cannot be induced.
* * *
mu·tant 'myüt-ənt adj of, relating to, or produced by mutationmutant n a mutant individual* * *
n.1. an individual in which a mutation has occurred, especially when the effect of the mutation is visible.2. a characteristic showing the effects of a mutation.• mutant adj.* * *
mu·tant (muґtənt) [L. mutare to change] 1. something, as an organism, cell, virus, or gene, that has undergone genetic mutation. 2. produced by mutation.
Medical dictionary. 2011.