Founder effect

Founder effect
The positive effect on gene frequency when a population (a colony) has only a small number of original settlers (founders) one or more of whom had that gene. For example, the gene for Huntington disease was introduced into the Lake Maracaibo region in Venezuela early in the 19th century. So there are now over a hundred persons with Huntington disease and at least 900 persons at risk for that deadly disease in that region, the largest known aggregation with the Huntington gene in the world.

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an altered gene frequency in a particular derived population relative to the parental population, as a result of establishment of the derived population by a small number of founders carrying limited genetic diversity.

Medical dictionary. 2011.

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Look at other dictionaries:

  • founder effect — founder effect. См. эффект основателя. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Founder effect — In population genetics, the founder effect refers to the loss of genetic variation when a new colony is established by a very small number of individuals from a larger population. It was first fully outlined by Ernst Mayr in 1952 [Provine, W.B.… …   Wikipedia

  • Founder-Effect — Beispiel: eine Stammpopulation (links) und drei mögliche Gründerpopulationen (rechts) Der Gründereffekt (Founder Effect) beschreibt eine genetische Abweichung einer isolierten Population oder Gründerpopulation (z. B. auf einer Insel) von der… …   Deutsch Wikipedia

  • founder effect — noun Date: 1970 the effect on the resulting gene pool that occurs when a new isolated population is founded by a small number of individuals possessing limited genetic variation relative to the larger population from which they have migrated …   New Collegiate Dictionary

  • founder effect — /ˈfaʊndər əfɛkt/ (say fownduhr uhfekt) noun the effect on the genetic composition of a population of organisms of having developed as a subpopulation derived from a few members of an original population isolated from that population; the genetic… …  

  • founder effect — The principle that when founders populate a new colony as an isolated entity, the population will contain only a small fraction of the total genetic variation of the parental population …   Dictionary of invertebrate zoology

  • founder effect — Biol. the accumulation of random genetic changes in an isolated population as a result of its proliferation from only a few parent colonizers. * * * …   Universalium

  • founder effect — noun A lessening of genetic variation when the entire population in question descends from a small number of founders …   Wiktionary

  • Founder effect —    Refers to the presence in a population of many individuals all with the same chromosome (or region of a chromosome) derived a single ancestor …   Forensic science glossary

  • founder effect — Biol. the accumulation of random genetic changes in an isolated population as a result of its proliferation from only a few parent colonizers …   Useful english dictionary

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