- 1. The condition in which a cell or tissue component takes on a color different from the dye solution with which it is stained. SYN: metachromatism (2). 2. A change in the characteristic color of certain basic thiazine dyes, such as toluidine blue, when the dye molecules are bound in proximate array to tissue polyanionic polymers, such as glycosaminoglycans. [meta- + G. chroma, color]
* * *meta·chro·ma·sia .met-ə-krō-'mā-zh(ē-)ə n1) the property of various tissues of staining in a different color (as when treatment with a blue aniline dye makes a cellular element red)2) the property of various biologic stains that permits a single dye to stain different tissue elements in different colors
* * *n.1. the property of a dye of staining certain tissues or cells a colour that is different from that of the stain itself.2. the variation in colour produced in certain tissue elements that are stained with the same dye.3. abnormal coloration of a tissue produced by a particular stain.• metachromatic adj.
* * *meta·chro·ma·sia (met″ə-kro-maґzhə) [meta- + Gr. chrōma color] 1. a condition in which tissues do not stain true with a given stain. 2. staining in which the same stain colors different tissues in different tints. 3. the change of color produced by staining.
Medical dictionary. 2011.