mechlorethamine hydrochloride

mechlorethamine hydrochloride
It is cytotoxic for all cells, but with a special affinity for bone marrow, lymphatic tissues, and rapidly proliferating cells of certain neoplasms. Used for the palliative treatment of Hodgkin disease, lymphosarcoma, and certain chronic leukemias. SYN: mustine hydrochloride.

* * *

mech·lor·eth·amine hy·dro·chlo·ride (mek″lor-ethґə-mēn) [USP] a cytotoxic alkylating agent of the nitrogen mustard group, used in the treatment of disseminated Hodgkin disease, some non-Hodgkin lymphomas, and mycosis fungoides; administered intravenously. It is also administered intraperitoneally, intrapericardially, and intrapleurally for the palliative treatment of malignant effusions. Called also HN2 and nitrogen mustard.

Medical dictionary. 2011.

Look at other dictionaries:

  • mechlorethamine hydrochloride — A drug used to treat some types of cancer and some precancerous skin conditions. It causes cancer cells to die by attaching to the DNA in the cells. Mechlorethamine hydrochloride is a type of alkylating agent. Also called mustine, mechlorethamine …   English dictionary of cancer terms

  • mechlorethamine — A drug used to treat some types of cancer and some precancerous skin conditions. It causes cancer cells to die by attaching to the DNA in the cells. Mechlorethamine is a type of alkylating agent. Also called mustine, mechlorethamine hydrochloride …   English dictionary of cancer terms

  • mechlorethamine — mech·lor·eth·amine .mek .lōr eth ə .mēn, .lȯr n a nitrogen mustard administered by injection in the form of its hydrochloride C5H11Cl2N·HCl in the palliative treatment of neoplastic diseases (as Hodgkin s disease and leukemia) …   Medical dictionary

  • mechlorethamine — ˌmeˌklōrˈethəˌmēn, lȯr , mə̇n noun Etymology: methyl + chloroethyl + amine : a nitrogen mustard C5H11Cl2N used in the form of its hydrochloride in the palliative treatment of some neoplastic diseases * * * /me klawr eth euh meen , klohr /, n.… …   Useful english dictionary

  • mustine hydrochloride — SYN: mechlorethamine hydrochloride …   Medical dictionary

  • procarbazine hydrochloride — An antineoplastic agent. * * * pro·car·ba·zine hy·dro·chlo·ride (pro kahrґbə zēn) [USP] an alkylating agent specific for the S phase of the cell cycle used as an antineoplastic, primarily in combination with mechlorethamine, vincristine …   Medical dictionary

  • Mechlorethamin — Strukturformel Allgemeines Freiname Mechlorethamin Andere Namen …   Deutsch Wikipedia

  • nitrogen mustard — n any of various toxic blistering compounds analogous to mustard gas but containing nitrogen instead of sulfur esp mechlorethamine * * * see chlormethine * * * 1. mechlorethamine hydrochloride. 2. any of a group of cytotoxic alkylating agents… …   Medical dictionary

  • HN2 — Symbol for nitrogen mustard. See nitrogen mustards, under mustard. * * * mechlorethamine; see mechlorethamine hydrochloride …   Medical dictionary

  • mustard — 1. The dried ripe seeds of Brassica alba (white m.) and B. nigra (black m.) (family Cruciferae). 2. SYN: m. gas. [O.Fr. moustarde, fr. L. mustum, must] black m. the dried ripe seed of Brassica nigra or of B. juncea; it is the source of allyl… …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”