liposome

liposome
1. A spherical particle of lipid substance suspended in an aqueous medium within a tissue. 2. Any small, roughly spherical artificial vesicle consisting of a lipid bilayer enclosing some of the suspending medium. [lipo- + G. soma, body]

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li·po·some 'lip-ə-.sōm, 'lī-pə- n
1) one of the fatty droplets in the cytoplasm of a cell
2) an artificial vesicle that is composed of one or more concentric phospholipid bilayers and is used esp. to deliver microscopic substances (as DNA or drugs) to body cells
li·po·so·mal .lip-ə-'sō-məl, .lī-pə- adj

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n.
a microscopic spherical membrane-enclosed vesicle or sac (20-30 nm in diameter) made artificially in the laboratory by the addition of an aqueous solution to a phospholipid gel. The membrane resembles a cell membrane and the whole vesicle is similar to a cell organelle. Liposomes can be incorporated into living cells and may be used to transport relatively toxic drugs into cancer cells, where they can exert their maximum effects. The cancerous organ is at a higher temperature than normal body temperature, so that when the liposome passes through its blood vessels the membrane melts and the drug (e.g. doxorubicin) is released. Liposomes are also undergoing clinical trials as vehicles in gene therapy for cystic fibrosis.

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lipo·some (lipґo-sōm) [lipo- + -some] a spherical particle in an aqueous medium, formed by a lipid bilayer enclosing an aqueous compartment.

Medical dictionary. 2011.

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  • liposome — [ lipozom ] n. m. • v. 1975; en angl. 1968; mot angl.; cf. lipo et some ♦ Petite vésicule artificielle formée de plusieurs feuillets phospholipidiques renfermant une solution aqueuse. Les liposomes peuvent véhiculer des substances actives vers… …   Encyclopédie Universelle

  • liposome — liposome. См. липосома. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • liposome —  Liposome  Липосома   Микроскопический сферический мембранный пузырек (диаметр около 2 мкм). Получается искусственно в лабораторных условиях путем добавления водного раствора к фосфолипидному гелю. Защитная оболочка этого пузырька напоминает… …   Толковый англо-русский словарь по нанотехнологии. - М.

  • liposome — ☆ liposome [lip′ə sōm΄, lī′pəsōm] n. [ LIPO + SOME ] a synthetic, microscopic globule consisting of layers of lipids encapsulating certain substances (as enzymes or drugs): used to introduce these substances into a cell or specified tissue …   English World dictionary

  • Liposome — A liposome is a tiny bubble (vesicle), made out of the same material as a cell membrane. Liposomes can be filled with drugs, and used to deliver drugs for cancer and other diseases. Membranes are usually made of phospholipids, which are molecules …   Wikipedia

  • Liposome — Unter einem Liposom versteht man eine bestimmte, kugelförmige Anordnung von oberflächenaktiven Molekülen in einer Flüssigkeit. Üblicherweise finden Phospholipide wie Lecithin als oberflächenaktive Substanzen Verwendung. Liposome bilden sich aus,… …   Deutsch Wikipedia

  • Liposome — Schéma d un liposome formé par des phospholipides en solution aqueuse. Un liposome est une vésicule artificielle formée par des bicouches lipidiques concentriques, emprisonnant entre elles des compartiments aqueux. On en obtient à partir d une… …   Wikipédia en Français

  • liposome — n. a microscopic spherical membrane enclosed vesicle or sac (20–30 nm in diameter) made artificially in the laboratory by the addition of an aqueous solution to a phospholipid gel. The membrane resembles a cell membrane and the whole vesicle is… …   The new mediacal dictionary

  • liposome — A synthetic microscopic spherical structure consisting of a phospholipid bilayer membrane containing a user defined aqueous solution. Liposomes can be used to transport relatively toxic drugs into diseased cells, where they can exert their… …   Glossary of Biotechnology

  • liposome entrapment — liposome entrapment. См. липосомная ловушка. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

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