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lipo·am·ide (lip″o-amґīd) lipoic acid in amide linkage with lysine side chains of enzymes of the α-ketoglutarate dehydrogenase, branched-chain α-keto acid dehydrogenase, and pyruvate dehydrogenase complexes (q.v.). Its reactive disulfide group and long, flexible chain enable it to transfer intermediates among the enzymes of each complex.

Medical dictionary. 2011.

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  • Lipoamide — Général Nom IUPAC 5 (1,2 dithiolan 3 yl)pentanamide Synonymes ami …   Wikipédia en Français

  • Lipoamide — Chembox new ImageFile = Lipoamide 2D skeletal.png ImageSize = IUPACName = OtherNames = Section1 = Chembox Identifiers CASNo = 940 69 2 PubChem = 863 SMILES = NC(=O)CCCC [C@@H] 1CCSS1 MeSHName = lipoamide Section2 = Chembox Properties Formula =… …   Wikipedia

  • lipoamide — The functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group …   Dictionary of molecular biology

  • lipoamide — noun The compound 6,8 dithiooctanoic amide …   Wiktionary

  • lipoamide dehydrogenase — An enzyme that regenerates lipoamide from the reduced form dihydrolipoamide …   Dictionary of molecular biology

  • lipoamide dehydrogenase — SYN: dihydrolipoamide dehydrogenase. * * * lipo·am·ide de·hy·dro·gen·ase (lip″o amґīd de hiґdro jən″ās) erroneous name for dihydrolipoyl dehydrogenase …   Medical dictionary

  • lipoamide disulfide — Oxidized lipoic acid in amide combination with the ε amino group of an l lysyl residue of pyruvic acid dehydrogenase …   Medical dictionary

  • lipoamide reductase — SYN: dihydrolipoamide dehydrogenase …   Medical dictionary

  • Pyruvate dehydrogenase (lipoamide) alpha 1 — PDB rendering based on 1ni4 …   Wikipedia

  • pyruvate — A salt or ester of pyruvic acid. active p. an intermediate formed in the oxidative decarboxylation of p.. Cf.:p. dehydrogenase (lipoamide). SYN: α lactyl thiamin pyrophosphate. p. carboxylase ligase …   Medical dictionary

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