keto acid

keto acid
An acid containing a ketone group (–CO–) in addition to the acid group(s); α-k. refers to a 2-oxo acid ( e.g., pyruvic acid); β-k. refers to a 3-oxo acid ( e.g., acetoacetic acid), etc. SYN: oxo acid.
- α-k. dehydrogenase one of several distinct multienzyme complexes that catalyzes the formation of an acyl-CoA derivative, CO2, and NADH from an α-k., NAD+, and coenzyme A; maple syrup urine disease results from several different inherited defects in the mitochondrial branched chain α-k. dehydrogenase complex.

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keto acid n a compound that is both a ketone and an acid

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ke·to ac·id (keґto) a carboxylic acid containing a carbonyl group, such as α-ketoglutaric acid.

Medical dictionary. 2011.

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Look at other dictionaries:

  • keto acid — noun : a compound that is both a ketone and an acid acetoacetic acid is a beta keto acid …   Useful english dictionary

  • Keto acid — Keto acids are organic acids containing a ketone functional group and a carboxylic acid group.Common types of keto acids include: *Alpha keto acids, or 2 oxo acids, such as pyruvic acid have the keto group adjacent to the carboxylic acid *Beta… …   Wikipedia

  • keto acid decarboxylase — ke·to ac·id de·car·box·y·lase (keґto asґid de″kahr bokґsə lās) α keto acid dehydrogenase …   Medical dictionary

  • keto acid — /kitoʊ ˈæsəd/ (say keetoh asuhd) noun a compound that is both a ketone and an acid, as acetoacetic acid …  

  • keto acid — noun Any carboxylic acid that also contains a ketone (carbonyl) group …   Wiktionary

  • branched-chain α-keto acid dehydrogenase complex — a multienzyme complex composed of 3 methyl 2 oxobutanoate dehydrogenase (2 methylpropanoyl transferring) [EC 1.2.4.4] (more commonly called branched chain α keto acid dehydrogenase), dihydrolipoyllysine residue (2 methylpropanoyl)transferase …   Medical dictionary

  • α-keto acid dehydrogenase complex — any of the enzyme complexes catalyzing the oxidative decarboxylation of α keto acids; see branched chain α keto acid dehydrogenase c., α ketoglutarate dehydrogenase c., and pyruvate dehydrogenase c …   Medical dictionary

  • Branched-chain alpha-keto acid dehydrogenase complex — protein Name=2 oxoisovalerate dehydrogenase (lipoamide) caption= width= HGNCid=8523 Symbol=OVD1A AltSymbols= EntrezGene=5014 OMIM= RefSeq= UniProt= PDB= ECnumber=1.2.4.4 Chromosome= Arm= Band= LocusSupplementaryData=The branched chain α keto acid …   Wikipedia

  • branched-chain α-keto acid dehydrogenase — branched chain α ke·to ac·id de·hy·dro·gen·ase (brancht chān keґto asґid de hiґdro jən ās) an enzyme of the oxidoreductase class that is a component of the multienzyme branched chain α keto acid dehydrogenase complex (q.v …   Medical dictionary

  • α-keto acid dehydrogenase — α ke·to ac·id de·hy·dro·gen·ase (keґto asґid de hiґdro jən ās) 1. see under complex. 2. the dehydrogenase component of any of the α keto acid dehydrogenase complexes …   Medical dictionary

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