kallikrein

kallikrein
A group of enzymes ( e.g., plasma, tissue, pancreatic, urinary, submandibular k.) that can convert kininogen by proteolysis to bradykinin or kallidin; trypsin and plasmin can also effect the conversion; plasma k. activates the Hageman factor and acts on kininogen. Tissue k. is a serine endopeptidase that can generate kallidin from kininogen. SYN: kininogenase, kininogenin.
- human glandular k. 3 (hK3) SYN: prostate-specific antigen.

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kal·li·kre·in .kal-ə-'krē-ən, kə-'lik-rē-ən n a hypotensive protease that liberates kinins from blood plasma proteins and is used therapeutically for vasodilation

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n.
one of a group of enzymes found in the blood and body fluids that act on certain plasma globulins to produce bradykinin and kallidin. See kinin.

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kal·li·kre·in (kal″ĭ-kreґin) any of several serine proteinases that cleave kininogens to form kinins, such as bradykinin and kallidin.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Kallikrein — 1 Bändermodell nach PDB  …   Deutsch Wikipedia

  • kallikrein — [kal΄i krē′in] n. any of a group of proteolytic enzymes in the blood, urine, etc. that release a kinin from various globulins * * * …   Universalium

  • kallikrein — [kal΄i krē′in] n. any of a group of proteolytic enzymes in the blood, urine, etc. that release a kinin from various globulins …   English World dictionary

  • Kallikrein — Kallikreins (tissue and plasma kallikrein) are peptidases (enzymes that cleave peptide bonds in proteins), a subgroup of the serine protease family.FunctionsThey liberate kinins (BK and KD) from the kininogens. [Oikonomopoulou, K., Hansen, K.K.,… …   Wikipedia

  • Kallikrein — Kal|li|kre|in [griech. kallíkreas = Bauchspeicheldrüse (eigtl. = schönes Fleisch); ↑ in (3)], das; s, e; Syn.: (internat. Freiname:) Kallidinogenase: Sammelbez. für aus inaktiven Vorstufen (Kallikreinogene als Zymogene) proteolytisch freigesetzte …   Universal-Lexikon

  • Kallikrein-related peptidase 4 — Größe …   Deutsch Wikipedia

  • kallikrein — noun Etymology: German, from Greek kallikreas sweetbread, pancreas, from kalli beautiful (from kallos beauty) + kreas flesh more at raw Date: 1930 a hypotensive protease that liberates kinins from blood plasma proteins and is used therapeutically …   New Collegiate Dictionary

  • kallikrein — Plasma serine proteases normally present as inactive prekallikreins which are activated by Hagemann factor. Act on kininogens to produce kinins. Contain an apple domain …   Dictionary of molecular biology

  • kallikrein — noun Any of a set of peptidases, a subgroup of the serine protease family …   Wiktionary

  • Kallikrein — Kalli|krei̱n [zu gr. ϰαλλιϰρεας = Bauchspeicheldrüse; eigtl. = schönes Fleisch] s; s: hormonartiger Wirkstoff der Bauchspeicheldrüse von blutdrucksenkender Wirkung u. Funktion …   Das Wörterbuch medizinischer Fachausdrücke

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