isotretinoin

isotretinoin
A retinoid used for treatment of severe recalcitrant cystic acne; a known human teratogen.

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iso·tret·i·noin .ī-sō-'tret-ə-.nȯin n a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, that inhibits sebaceous gland function and keratinization, and that is administered in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects see ACCUTANE

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n.
a drug related to vitamin A (see retinoid) and used in the treatment of severe acne that has failed to respond to other treatment. It is administered by mouth or topically. Possible side-effects include dry skin, nose bleeds, eyelid and lip inflammation, muscle, joint, and abdominal pains, diarrhoea, and some disturbances of vision. Trade names: Isotrex, Roaccutane.

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iso·tret·i·noin (i″so-tretґĭ-no-in) (-noin) 13-cis-retinoic acid, used systemically for treatment of severe cystic and conglobulate acne; it inhibits the secretion of sebum and alters the lipid composition of the skin surface.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Isotretinoin — Systematic (IUPAC) name (13cis) …   Wikipedia

  • Isotretinoin — Strukturformel Allgemeines Freiname Isotretinoin Andere Namen …   Deutsch Wikipedia

  • isotretinoin — ˌīsō.ˈtred.əˌnȯin, ˈtret noun ( s) Etymology: is + tretinoin (herein) : a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, that inhibits sebaceous gland function and keratinization, and that is used in the treatment of… …   Useful english dictionary

  • isotretinoin — noun Date: 1980 a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, inhibits sebaceous gland function and keratinization, and is used in the treatment of severe inflammatory acne …   New Collegiate Dictionary

  • isotretinoin — /uy soh tri tin oh in, oyn/, n. Pharm. a yellowish orange to orange crystalline powder, C20H28O2, used in the treatment of cystic acne. [ISO + tretinoin a name for retinoic or Vitamin A acid, equiv. to t (of uncert. derivation) + retino(ic acid)… …   Universalium

  • isotretinoin — noun A medication used in the treatment of acne and cancer …   Wiktionary

  • Isotretinoin — I|so|tre|ti|no|in [↑ Tretinoin] ↑ Retinoesäure …   Universal-Lexikon

  • isotretinoin — iso·tret·i·no·in …   English syllables

  • isotretinoin — n. a drug related to vitamin A (see retinoid) and used in the treatment of severe acne that has failed to respond to other treatment. It is administered by mouth or topically. Possible side effects include dry skin, nose bleeds, eyelid and lip… …   The new mediacal dictionary

  • isotretinoin — A drug that belongs to the family of drugs called retinoids. It is used in the treatment of acne and psoriasis and is being studied in cancer prevention. Also called 13 cis retinoic acid …   English dictionary of cancer terms

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