Conferring on normal cells cultured in vitro the property of an infinite lifespan, as from spontaneous mutation, by exposure to chemical carcinogens, or by viral infection. I. of primary cells in culture is the first of several steps in the expression of transforming genes of DNA tumor viruses, of retrovirus oncogenes, and cellular oncogenes derived from human cancer cells.

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im·mor·tal·i·za·tion (ĭ-mor″təl-ĭ-zaґshən) acquisition of immunity to normal limitations on growth or life span, sometimes achieved by animal cells in vitro or by tumor cells; causes may be spontaneous mutation, exposure to chemical carcinogens, or viral infection.

Medical dictionary. 2011.

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  • Immortalization — Im*mor tal*i*za tion, n. The act of immortalizing, or state of being immortalized. [1913 Webster] …   The Collaborative International Dictionary of English

  • immortalization — immortalization. См. иммортализация. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • immortalization — index dedication, preservation, remembrance (commemoration) Burton s Legal Thesaurus. William C. Burton. 2006 …   Law dictionary

  • immortalization — (n.) c.1600, noun of action or state from IMMORTALIZE (Cf. immortalize) …   Etymology dictionary

  • immortalization — (Amer.) n. act of immortalizing, being immortalized (also immortalisation) …   English contemporary dictionary

  • immortalization — Escape from the normal limitation on growth of a finite number of division cycles (the Hayflick limit), by variants in animal cell cultures, and cells in some tumours. Immortalization in culture may be spontaneous, as happens particularly readily …   Dictionary of molecular biology

  • immortalization — noun see immortalize …   New Collegiate Dictionary

  • immortalization — See immortalize. * * * …   Universalium

  • immortalization — noun The act of immortalizing, or state of being immortalized …   Wiktionary

  • immortalization — im·mor·tal·iza·tion …   English syllables

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