imipenem

A thienamycin antibiotic with broad spectrum activity used, in combination with cilastin, to treat a variety of infections.

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im·i·pen·em .im-ə-'pen-əm n a semisynthetic beta-lactam C₁₂H₁₇N₃O₄S·H₂O that is derived from an antibiotic produced by a bacterium of the genus Streptomyces (S. cattleya) and is effective against gram-negative and gram-positive bacteria

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im·i·pen·em (im″ĭ-penґəm) [USP] a broad-spectrum antibiotic of the carbapenem group, having activity against a wide range of gram-positive and gram-negative organisms. Because it is hydrolyzed by a dipeptidase occurring in the proximal renal tubule, it is administered with the dipeptidase inhibitor cilastatin sodium.