imidazole

A five-membered heterocyclic compound occurring in l-histidine and other biologically important compounds.

- i. alkaloids alkaloids containing one or more i. moieties as part of its structure ( E.G., pilocarpine).

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im·id·az·ole .im-ə-'daz-.ōl n

1) a white crystalline heterocyclic base C₃H₄N₂ that is an antimetabolite related to histidine

2) any of a large class of derivatives of imidazole including histidine and histamine

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n.

one of a group of chemically related antifungal drugs that are also effective against a wide range of bacteria; some (e.g. tiabendazole and mebendazole) are also used as anthelmintics. The group includes econazole, clotrimazole, ketoconazole, and miconazole. They are administered by mouth or externally as creams.

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im·id·az·ole (im″id-azґōl) 1. a five-membered heterocyclic organic compound containing two nitrogen atoms in the ring: It is a type of azole, and is an antimetabolite and inhibitor of histamine and is used as an insecticide. 2. any of a class of fungistatic compounds containing such a ring, a subset of the class of azole antifungals, effective against a wide range of fungi; they alter cell membrane functions and permeability by inhibiting the biosynthesis of ergosterol.