hydroxyacylglutathione hydrolase
- hydroxyacylglutathione hydrolase
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hy·droxy·ac·yl·glu·ta·thi·one hy·dro·lase (hi-drok″se-a″səl-gloo″tə-thiґōn hiґdro-lās) [EC 3.1.2.6] an enzyme of the hydrolase class that catalyzes the cleavage of a hydroxyacylglutathione compound to the corresponding hydroxy acid and glutathione, specifically converting lactoylglutathione to lactic acid as the last step in the conversion of methylglyoxal to lactic acid. The enzyme is found in red cells and other animal tissues. See also glyoxalase.
Medical dictionary.
2011.
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Hydroxyacylglutathione hydrolase — In enzymology, a Hydroxyacylglutathione hydrolase (EC number|3.1.2.6) is an enzyme that catalyzes the chemical reaction:(R) S lactoylglutathione + water ightleftharpoons glutathione + a 2 hydroxy carboxylateHence, this enzyme has two substrate,… … Wikipedia
hydroxyacylglutathione hydrolase — noun An enzyme involved in pyruvate metabolism … Wiktionary
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glyoxalase — An enzyme, lactoylglutathione lyase (g. I) or hydroxyacylglutathione hydrolase (g. II), in red cells and other tissues that converts glyoxal and substituted glyoxals bound to glutathione into the corresponding free hydroxy acid s (g. II) or… … Medical dictionary