homotropic

homotropic
Referring to the binding of the same ligand to a macromolecule; E.G., the binding of four O2 to hemoglobin is h. cooperativity.

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ho·mo·tro·pic .hō-mə-'trō-pik, .häm-ə- adj characterized by enzyme activity in which the substrate binds to the enzyme at two different sites of which one is the normal reactive site and the other is an allosteric site <\homotropic enzymes> <\homotropic interaction> compare HETEROTROPIC

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ho·mo·tro·pic (hoґmo-tro″pik) [homo- + -tropic] pertaining to an allosteric enzyme that is modulated by its usual substrate. Cf. heterotropic.

Medical dictionary. 2011.

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