hexokinase

hexokinase
A phosphotransferase present in yeast, muscle, brain, and other tissues that catalyzes the ATP-dependent phosphorylation of d-glucose and other hexoses to form d-glucose 6-phosphate (or other hexose 6-phosphates); the first step in glycolysis; a deficiency of h. can result in hemolytic anemia and impaired glycolysis.

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hexo·ki·nase .hek-sə-'kī-.nās, -.nāz n any of a group of enzymes that accelerate the phosphorylation of hexoses (as in the formation of glucose-6-phosphate from glucose and ATP) in carbohydrate metabolism

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n.
an enzyme that catalyses the conversion of glucose to glucose-6-phosphate. This is the first stage of glycolysis.

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hexo·ki·nase (hek″so-kiґnās) [EC 2.7.1.1] an enzyme of the transferase class that catalyzes the phosphorylation of hexose at the 6 carbon, the initial step in the cellular utilization of free hexoses. The enzyme occurs in all tissues and exists as various isozymes. Those in brain and muscles are relatively nonspecific; glucose, fructose, and mannose are effective substrates at low concentrations. The liver isozyme, often designated type IV, is called also glucokinase because it is more specific for glucose.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Hexokinase — Structure de l’hexokinase 1 cristallisée de Kluyveromyces lactis.   …   Wikipédia en Français

  • Hexokinase — Hex o*kin ase, n. [Hexose + kinase.] (Biochem.) an enzyme catalyzing the transfer of a phosphate residue from ATP to a hexose, as in the formation of glucose 6 phosphate from glucose. [PJC] …   The Collaborative International Dictionary of English

  • hexokinase — hexokinase. См. гексокиназа. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Hexokinase — A hexokinase is an enzyme that phosphorylates a six carbon sugar, a hexose, to a hexose phosphate. In most tissues and organisms, glucose is the most important substrate of hexokinases, and glucose 6 phosphate the most important product.… …   Wikipedia

  • Hexokinase — Glucokinase Vorhandene Strukturdaten: 1glk …   Deutsch Wikipedia

  • hexokinase — heksokinazė statusas T sritis chemija apibrėžtis Fermentas, katalizuojantis heksozių fosforilinimą esant ATP. atitikmenys: angl. hexokinase rus. гексокиназа …   Chemijos terminų aiškinamasis žodynas

  • hexokinase — noun Etymology: hexose + kinase Date: 1930 any of a group of enzymes that accelerate the phosphorylation of hexoses (as in the formation of glucose 6 phosphate from glucose and ATP) in carbohydrate metabolism …   New Collegiate Dictionary

  • hexokinase — Enzyme that catalyses the transfer of phosphate from ATP to glucose to form glucose 6 phosphate, the first reaction in the metabolism of glucose via the glycolytic pathway …   Dictionary of molecular biology

  • hexokinase — /hek seuh kuy nays, nayz/, n. Biochem. an enzyme that catalyzes the phosphorylation of hexose sugars. [1925 30; HEXO(SE) + KINASE] * * * …   Universalium

  • hexokinase — noun Any enzyme that catalyses the phosphorylation of a hexose …   Wiktionary

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