A molecule that is incapable, alone, of causing the production of antibodies but can, however, combine with a larger antigenic molecule called a carrier. A h.-carrier complex can stimulate production of antibodies, some of which combine with the h. portion of the complex. SEE ALSO: h. inhibition of precipitation. SYN: incomplete antigen, partial antigen. [G. hapto, to fasten, bind]
- conjugated h. a h. that may cause the production of antibodies when it has been covalently linked to protein. SYN: conjugated antigen.
- Forssman h. a glycolipid from mammalian organs; it is a ceramide pentasaccharide. Cf.:Forssman antibody, Forssman antigen.
- half h. half-h..

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hap·ten 'hap-.ten n a small separable part of an antigen that reacts specif. with an antibody but is incapable of stimulating antibody production except in combination with an associated protein molecule
hap·ten·ic hap-'ten-ik adj
hap·ten·at·ed 'hap-tə-.nāt-əd adj

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hap·ten (hapґtən) [Ger., from Gr. haptein to fasten] a small molecule, not antigenic by itself, that can react with antibodies of appropriate specificity and elicit the formation of such antibodies when conjugated to a larger antigenic molecule, usually a protein, called in this context the carrier or schlepper. Antibody production involves activation of B lymphocytes by the hapten and helper T lymphocytes by the carrier.

Medical dictionary. 2011.

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  • hapten — hapten. См. полуантиген. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • hapten — HAPTÉN s. n. substanţă care, asociată cu o protidă, îi conferă calităţile unui antigen. (< fr. haptène) Trimis de raduborza, 15.09.2007. Sursa: MDN …   Dicționar Român

  • hapten — [hap′tēn΄hap′ten΄] n. [Ger < Gr haptein, to fasten, touch + Ger en, ENE] a compound which, when coupled with a protein or other molecule, can cause the formation of antibodies: also haptene [hap′tēn΄] haptenic [hap ten′ik] adj …   English World dictionary

  • Hapten — A hapten is a small molecule which can elicit an immune response only when attached to a large carrier such as a protein; the carrier may be one which also does not elicit an immune response by itself. (Generally, only large molecules, infectious …   Wikipedia

  • hapten — Could be considered an isolated epitope: although a hapten (by definition) has an antibody directed against it, the hapten alone will not induce an immune response if injected into an animal, it must be conjugated to a carrier (usually a protein) …   Dictionary of molecular biology

  • hapten — /hap ten/, n. Immunol. a substance having a single antigenic determinant that can react with a previously existing antibody but cannot stimulate more antibody production unless combined with other molecules; a partial antigen. Also, haptene /hap… …   Universalium

  • Hapten — Haptene sind kleine organische Moleküle, wie z. B. Atrazin oder Digoxigenin. Sie gehören zur Gruppe der Antigene, unterscheiden sich jedoch von diesen dadurch, dass sie nicht alleine in der Lage sind, eine Immunreaktion hervorzurufen. Dies ist… …   Deutsch Wikipedia

  • hapten — /ˈhæptən/ (say haptuhn) noun a small molecule which cannot by itself elicit an immune response but which needs to be attached to a larger carrier in order to do so. {German hapten, from Greek haptein to fasten} …   Australian-English dictionary

  • hapten — noun Etymology: German, from Greek haptein to fasten Date: 1921 a small separable part of an antigen that reacts specifically with an antibody but is incapable of stimulating antibody production except in combination with a carrier protein… …   New Collegiate Dictionary

  • hapten — (hap ten) A molecule not immunogenic by itself but that, when coupled to a macromolecular carrier, can elicit antibodies directed against itself …   Dictionary of microbiology

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