An infectious granuloma that is characteristic of tertiary syphilis, but does not always develop, and that may be solitary (as large as 8–10 cm in diameter) or multiple and diffusely scattered (1 mm or less in diameter). Gummas are characterized by an irregular central portion that is firm, sometimes partially hyalinized, and consisting of coagulative necrosis in which “ghosts” of structures may be recognized; a poorly defined middle zone of epithelioid cells, with occasional multinucleated giant cells; and a peripheral zone of fibroblasts and numerous capillaries, with infiltrated lymphocytes and plasma cells. As gummas become older, an irregular scar or rounded fibrous nodule persists. SYN: syphiloma. [L. gummi, gum, fr. G. kommi]

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gum·ma 'gəm-ə n, pl gummas also gum·ma·ta 'gəm-ət-ə a tumor of gummy or rubbery consistency that is characteristic of the tertiary stage of syphilis
gum·ma·tous -ət-əs adj

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a small soft tumour, characteristic of the tertiary stage of syphilis, that occurs in connective tissue, the liver, brain, testes, heart, or bone.

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gum·ma (gumґə) pl. gummas, gumґmata [L. gummi gum] 1. a chronic focal area of inflammatory destruction in tertiary syphilis from localization of Treponema pallidum in a tissue. The lesion is indolent and has a center of rubbery, gray-white coagulation necrosis surrounded by epithelioid cells, fibroblastic cells, and sometimes giant cells. Gummata vary in size from microscopic to large and tumorlike; they may be single or multiple and may involve any organ or tissue, although most commonly they affect mucocutaneous tissues, the liver, bones, or testes. Called also syphiloma. 2. late benign syphilis.

Gumma of the palate.

Medical dictionary. 2011.

Look at other dictionaries:

  • Gumma — (or Guma) is both a medical term and the name of several different geographical entities:* Gumma (pathology) is a characteristic tissue nodule found in the tertiary stage of syphilis. * The Kingdom of Gumma (also spelled Guma) is a former kingdom …   Wikipedia

  • Gumma — steht für: Königreich Gumma, ein historisches Reich in Äthiopien Präfektur Gunma, eine japanische Präfektur in modifizierter Hepburn Umschrift eine Geschwulstart (Pl. Gummata oder auch Gummen), die bei Syphilis im Tertiärstadium auftritt, siehe… …   Deutsch Wikipedia

  • Gumma — Gum ma (g[u^]m m[.a]), n.; pl. {Gummata}. [NL. So called from its gummy contents See {Gum}.] (Med.) A kind of soft tumor, usually of syphilitic origin. [1913 Webster] …   The Collaborative International Dictionary of English

  • Gumma — (Mehrz. Gummate), 1) schleimartiges Gewächs; 2) so v.w. Gummigeschwulst …   Pierer's Universal-Lexikon

  • Gumma — Gumma, s. Syphilis …   Meyers Großes Konversations-Lexikon

  • Gumma — Gumma, s. Syphilis …   Kleines Konversations-Lexikon

  • gumma — [gum′ə] n. pl. gummas or gummata [gum′ə tə] [ModL < L gummi, GUM1] a soft, rubbery tumor occurring in various organs or tissues, esp. in the late stages of syphilis gummatous adj …   English World dictionary

  • gumma — I s ( n, gummor) gammal kvinna II v ( de, t) gumma ihop klistra ihop, gumma upp håret fästa upp håret i knut …   Clue 9 Svensk Ordbok

  • gumma — noun (plural gummas; also gummata) Etymology: New Latin gummat , gumma, from Late Latin, gum, alteration of Latin gummi gum Date: circa 1722 a tumor of gummy or rubbery consistency that is characteristic of the tertiary stage of syphilis •… …   New Collegiate Dictionary

  • gumma — gummatous, adj. /gum euh/, n., pl. gummas, gummata /gum euh teuh/. Pathol. a rubbery, tumorlike lesion associated with tertiary syphilis. [1715 25; < NL; see GUM1] * * * ▪ prefecture, Japan       landlocked ken (prefecture) …   Universalium

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