guanethidine sulfate

guanethidine sulfate
A potent antihypertensive agent. It appears to interfere with the release of the chemical mediator (norepinephrine) at the sympathetic neuroeffector junction; it does not produce ganglionic or parasympathetic blockade with recommended doses. In ophthalmology, it is used topically for the treatment of glaucoma and to counteract eyelid retraction in Graves disease.

Medical dictionary. 2011.

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  • guanethidine — noun Etymology: guanidine + eth Date: 1959 a drug C10H22N4 used especially in the form of its sulfate to treat hypertension …   New Collegiate Dictionary

  • guanethidine — gua·neth·i·dine gwä neth ə .dēn n a drug used esp. in the form of its sulfate C10H22N4·H2SO4 to treat severe high blood pressure * * * n. a drug that is used to reduce high blood pressure (see sympatholytic). It is administered by mouth; common… …   Medical dictionary

  • guanethidine — gwäˈnethə̇ˌdēn, ə̇də̇n noun ( s) Etymology: guanidine + eth : a synthetic guanidine derivative C10H22N4 used especially in the form of its sulfate in treating severe high blood pressure …   Useful english dictionary

  • debrisoquine sulfate — An antihypertensive agent resembling guanethidine; also used in drug metabolism studies …   Medical dictionary

  • guanadrel sulfate — An antihypertensive drug similar in action to guanethidine. * * * gua·na·drel sul·fate (gwahґnə drel) [USP] an adrenergic neuron blocking agent, used in the treatment of hypertension; administered orally …   Medical dictionary

  • debrisoquin sulfate — deb·ris·o·quin sul·fate (deb risґo kwin) an antihypertensive agent having actions and uses similar to those of guanethidine; administered orally. Spelled also debrisoquine …   Medical dictionary

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