granzymes

granzymes
Proteases with serine esterase activities that represent most of the granule content of T cytotoxic cells. It is not known if these enzymes are required for killing by the T cytotoxic cell. [granule + -zyme]

Medical dictionary. 2011.

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  • Granzyme — Granzymes are serine proteases that are released by cytoplasmic granules within cytotoxic T cells and natural killer cells. Their purpose is to induce apoptosis within virus infected cells, thus destroying them.cite journal |author=Bots M, Medema …   Wikipedia

  • Natural killer cell — Latin lymphocytus K Code TH H2.00.04.1.02006 Natural killer cells (or NK cells) are a type of cytotoxic lymphocyte that constitute a major component of the innate immune system. NK cells play a major role in the rejection of …   Wikipedia

  • GZMA — Granzyme A (granzyme 1, cytotoxic T lymphocyte associated serine esterase 3), also known as GZMA, is a human gene.cite web | title = Entrez Gene: GZMA granzyme A (granzyme 1, cytotoxic T lymphocyte associated serine esterase 3)| url =… …   Wikipedia

  • Granzyme — Les granzymes sont une famille de protéines, des sérines protéases. Les granzymes sont un des moyens d action des cellules immunitaires cytotoxiques (cellule T et NK) pour lyser leur cible. La perforine permet aux granzymes d entrer dans les… …   Wikipédia en Français

  • Cytotoxic T cell — Antigen presentation stimulates T cells to become either cytotoxic CD8+ cells or helper CD4+ cells. A cytotoxic T cell (also known as TC, Cytotoxic T Lymphocyte, CTL, T Killer cell, cytolytic T cell, CD8+ T cells or killer T cell) belongs to a… …   Wikipedia

  • GZMK — Granzyme K (granzyme 3; tryptase II), also known as GZMK, is a human gene.cite web | title = Entrez Gene: GZMK granzyme K (granzyme 3; tryptase II)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=3003|… …   Wikipedia

  • GZMM — Granzyme M (lymphocyte met ase 1), also known as GZMM, is a human gene.cite web | title = Entrez Gene: GZMM granzyme M (lymphocyte met ase 1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=3004| accessdate …   Wikipedia

  • Granzyme — ist ein Kofferwort aus Granula und Enzymen und beschreibt Proteasen, die in den intrazellulären Granula von Abwehrzellen aktiv sind, in besonderem Maße in cytotoxischen T Zellen. Sie werden maßgeblich von dem Enzym Perforin unterstützt. Es sind… …   Deutsch Wikipedia

  • Antibody-dependent cell-mediated cytotoxicity — (ADCC) is a mechanism of cell mediated immunity whereby an effector cell of the immune system actively lyses a target cell that has been bound by specific antibodies. It is one of the mechanisms through which antibodies, as part of the humoral… …   Wikipedia

  • NKCell DRAFT — Natural killer (NK) cells are a form of cytotoxic lymphocyte which constitute a major component of the innate immune system. NK cells play a major role in the host rejection of both tumours and virally infected cells. They were named natural… …   Wikipedia

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