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gly·cin·a·mide ri·bo·nu·cleo·tide (gli-sinґə-mīd ri″bo-nooґkle-o-tīd) an intermediate of purine biosynthesis in which glycine is linked to the amino group of phosphoribosylamine.Medical dictionary. 2011.
glycinamide ribonucleotide formyltransferase inhibitor — A drug that blocks DNA synthesis and may prevent tumor growth. It is being studied as a treatment for cancer … English dictionary of cancer terms
glycineamide ribonucleotide, glycinamide ribonucleotide — An intermediate in purine biosynthesis, in which the amide nitrogen of glycineamide is linked to the C 1 of a ribosyl moiety … Medical dictionary
phosphoribosylglycineamide synthetase — Glycinamide ribonucleotide synthetase; an enzyme that reacts glycine with ribosylamine 5 phosphate and ATP to form ADP, orthophosphate, and phosphoribosylglycineamide in the course of purine biosynthesis … Medical dictionary
Phosphoribosylamine-glycine ligase — In enzymology, a phosphoribosylamine glycine ligase (EC number|6.3.4.13) is an enzyme that catalyzes the chemical reaction:ATP + 5 phospho D ribosylamine + glycine ightleftharpoons ADP + phosphate + N1 (5 phospho D ribosyl)glycinamideThe 3… … Wikipedia
List of oncology-related terms — This is a list of terms related to oncology. The original source for this list was the U.S. National Cancer Institute s public domain Dictionary of Cancer Terms . NOTOC 1 * 10 propargyl 10 deazaaminopterin * 12 O tetradecanoylphorbol 13 acetate * … Wikipedia
Protein domain — Pyruvate kinase, a protein from three domains (PDB 1pkn) A protein domain is a part of protein sequence and structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three… … Wikipedia
Pemetrexed — drugbox IUPAC name = 2 [4 [2 (4 amino 2 oxo 3,5,7 triazabicyclo [4.3.0] nona 3,8,10 trien 9 yl)ethyl] benzoyl] aminopentanedioic acid CAS number = 137281 23 3 ATC prefix = L01 ATC suffix = BA04 ATC supplemental = PubChem = 60843 DrugBank =… … Wikipedia
AG2037 — A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called glycinamide ribonucleotide formyl transferase inhibitors … English dictionary of cancer terms
