glucokinase

glucokinase
Phosphotransferase that catalyzes the conversion of d-glucose and ATP to d-glucose 6-phosphate and ADP; the liver enzyme has a higher Km value for d-glucose than does hexokinase and is not strongly inhibited by the product d-glucose 6-phosphate.

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glu·co·ki·nase -'kī-.nās, -.nāz n a hexokinase found esp. in the liver that catalyzes the phosphorylation of glucose in metabolic processes

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n.
an enzyme (a hexokinase), found in the liver, that catalyses the conversion of glucose to glucose-6-phosphate. This is the first stage of glycolysis.

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glu·co·ki·nase (gloo″ko-kiґnās) [EC 2.7.1.2] 1. an enzyme of the transferase class that catalyzes the phosphorylation of D-glucose at the 6 carbon. The enzyme is found in invertebrates and microorganisms and is highly specific for glucose. 2. hexokinase, type IV (liver).

Medical dictionary. 2011.

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  • Glucokinase — (hexokinase 4) Based on PDB entry 1GLK …   Wikipedia

  • Glucokinase — Bändermodell der menschlichen Glucokinase mit Glucose und Aktivator MRK als Kalotten, nach PD …   Deutsch Wikipedia

  • Glucokinase — Général Synonymes EC …   Wikipédia en Français

  • glucokinase — glucokinase. См. глюкокиназа. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Glucokinase-Regulator — Masse/Länge Primärstruktur 624 Aminosäuren …   Deutsch Wikipedia

  • Glucokinase regulatory protein — protein Name = caption = width = HGNCid = 4196 Symbol = GCKR AltSymbols = EntrezGene = 2646 OMIM = 600842 RefSeq = NM 001486 UniProt = Q14397 PDB = ECnumber = Chromosome = 2 Arm = p Band = 23 LocusSupplementaryData = The glucokinase regulatory… …   Wikipedia

  • glucokinase — noun Date: 1950 a hexokinase found especially in the liver that catalyzes the phosphorylation of glucose …   New Collegiate Dictionary

  • glucokinase — /glooh koh kuy nays, nayz/, n. Biochem. an enzyme, found in all living systems, that serves to catalyze the phosphorylation of gluconic acid. [GLUC(ONIC ACID) + O + KINASE] * * * …   Universalium

  • glucokinase — noun A hexokinase isozyme that facilitates phosphorylation of glucose to glucose 6 phosphate, occurring in cells in the liver, pancreas, gut, and brain of humans and most other vertebrates …   Wiktionary

  • Glucokinase — Glu|co|ki|na|se [↑ Glucose u. ↑ Kinase] in der Leber aktive Phosphotransferase, die Glucose in Glucose 6 phosphat umwandelt …   Universal-Lexikon

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