DNA amplification

DNA amplification
The production of multiple copies of a sequence of DNA. Repeated copying of a piece of DNA. DNA amplification plays a role in cancer cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals and sometimes environmental events. Amplification can occur in vivo (in the living individual) or in vitro (literally "in glass", or in a plastic vessel in the laboratory).

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1. an in vitro technique used to increase the number of copies of a specific segment of DNA to aid in its detection; see nucleic acid amplification technique, under technique. 2. a term sometimes used to denote in vivo gene amplification, particularly that associated with malignancy.

Medical dictionary. 2011.

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