ganciclovir

ganciclovir
An antiviral agent used in the treatment of opportunistic cytomegalovirus infections.

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gan·ci·clo·vir gan-'sī-klə-(.)vir n an antiviral drug C9H13N5O4 related to acyclovir and used esp. in the treatment of cytomegalovirus retinitis in immunocompromised patients called also DHPG

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n.
an antiviral drug used to treat severe cytomegalovirus infections, mainly in patients with AIDS. It is administered by mouth or injection or as eye drops. Possible side-effects include nausea, vomiting, diarrhoea, infertility, confusion, seizures, and disturbance of bone marrow blood-cell production. Trade names: Cymevene, Virgan.

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gan·ci·clo·vir (gan-siґklo-vir) a derivative of acyclovir that inhibits replication of herpesviruses. When used for the treatment of cytomegalovirus infections, ganciclovir is preferentially phosphorylated in infected cells, with the phosphorylated form inhibiting viral DNA synthesis. Administered orally and by intravitreal implant. Called also DHPG.

Medical dictionary. 2011.

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  • Ganciclovir — Systematic (IUPAC) name 2 amino 9 {[(1,3 dihydroxypropan 2 yl)oxy]methyl} 6,9 dihydro 3H purin 6 one Clinical data …   Wikipedia

  • Ganciclovir — Ganciclovir. El ganciclovir es un antiviral utilizado para el tratamiento de las infecciones causadas por citomegalovirus, especialmente para las retinitis causadas por este tipo de virus en pacientes inmunodeprimidos como los enfermos de… …   Wikipedia Español

  • ganciclovir — un fármaco antivírico utilizado en el tratamiento y prevención de las enfermedades producidas por citomegalovirus en pacientes inmunodeprimidos El ganciclovir forma parte de un sistema denominado (HSV TK)/(GCV) [Tirosina Kinasa del Herpes Virus… …   Diccionario médico

  • Ganciclovir — Général Nom IUPAC 2 amino 9 {[3 hydroxy 2 (hydroxyméthyl)propoxy]méthyl} 3,9 dihydro 6H purin 6 one …   Wikipédia en Français

  • Ganciclovir — Strukturformel Allgemeines Freiname Ganciclovir …   Deutsch Wikipedia

  • Ganciclovir — ГАНЦИКЛОВИР ( Ganciclovir ). 9 (1,3 Дигидрокси 2 пропоксиметил) гуанин, или [[2 Гидрокси 1 (гидроксиметил)этокси]метил] гуанин. Выпускается в виде мононатриевой соли. Синоним: Cymevene. Белый или почти белый кристаллический порошок, растворимый в …   Словарь медицинских препаратов

  • ganciclovir — Eng. Ganciclovir Antivírico análogo de la guanosina y de estructura similar al aciclovir aunque con un espectro de acción más amplio que incluye los virus de Epstein Barr y citomegalovirus. En Oftalmología se usa principalmente por vía… …   Diccionario de oftalmología

  • ganciclovir — An antiviral agent used to prevent or treat cytomegalovirus infections that may occur when the body s immune system is suppressed. In gene therapy, ganciclovir is used with an altered herpes simplex virus 1 gene to kill advanced melanoma cells… …   English dictionary of cancer terms

  • ganciclovir — ganˈsīklə(ˌ)vir noun ( s) Etymology: perhaps from guanosine + ciclovir, alteration of cyclovir (as in acyclovir herein) : an antiviral drug C9H13N5O4 related to acyclovir and used especially in the treatment of cytomegalovirus retinitis in… …   Useful english dictionary

  • ganciclovir sodium — the monosodium salt of ganciclovir, used for the treatment of cytomegalovirus retinitis in immunocompromised patients; administered intravenously or by intravitreal injection …   Medical dictionary

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