formazan

formazan
A water-insoluble colored compound of the general structure, RNH—N=CR′—N=NR″, formed by reduction of a tetrazolium salt in the histochemical demonstration of oxidative enzymes; the R's are usually phenyl groups; examples include neotetrazolium, blue tetrazolium, and nitro blue tetrazolium.

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form·a·zan 'fȯr-mə-.zan n a hypothetical hydrazone CH4N4 related to formic acid and known only in the form of intensely colored derivatives of which some are obtained from colorless compounds by the reducing action of living tissues and serve as indicators of viability by color production also any of these derivatives

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for·ma·zan (forґmə-zan) reduced nitroblue tetrazolium that is dark blue and water-insoluble; the reduction process is the basis of the nitroblue tetrazolium test (see under test).

Medical dictionary. 2011.

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  • Formazan — dyes are artificial chromogenic substrates for dehydrogenases and reductases. They are formed from reduction of tetrazolium salts, including INT (2 (4 Iodophenyl) 3 (4 nitrophenyl) 5 phenyl 2H tetrazolium chloride), MTT (3 (4, 5 dimethyl 2… …   Wikipedia

  • Formazan — Strukturformel Allgemeines Name Triphenyltetrazoliumchlorid Andere Namen …   Deutsch Wikipedia

  • formazan — formazanas statusas T sritis chemija formulė NH₂N=CHN=NH atitikmenys: angl. formazan rus. формазан …   Chemijos terminų aiškinamasis žodynas

  • formazan — ˈfȯrməˌzan noun ( s) Etymology: form + az + an : a hypothetical hydrazone HN . NCH . NNH2 related to formic acid and known only in the form of intensely colored derivatives (as triphenyl formazan) that are obtained either from hydrazones by… …   Useful english dictionary

  • formazan — noun the organic nitrogen compound HN …   Wiktionary

  • Formazan — For|m|a|zan [↑ Form u. ↑ Az ], das; s, e: Gruppenbez. für Verb. der allg. Formel H2N N=CH N=NH, die einigen Farbstoffen zugrunde liegt, z. B. 1,3,5 Triphenylformazan (↑ Tetrazoliumsalz) …   Universal-Lexikon

  • formazan — form·a·zan …   English syllables

  • MTT assay — is a laboratory test and a standard colorimetric assay (an assay which measures changes in color) for measuring the activity of enzymes that reduce MTT to formazan, giving a purple color. This mostly happens in mitochondria, and as such it is in… …   Wikipedia

  • Tetrazolium — Strukturformel Allgemeines Name Triphenyltetrazoliumchlorid Andere Namen …   Deutsch Wikipedia

  • Tetrazolium Salz — Strukturformel Allgemeines Name Triphenyltetrazoliumchlorid Andere Namen …   Deutsch Wikipedia

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