fluoro-2,4-dinitrobenzene

fluoro-2,4-dinitrobenzene
A reagent used to combine with the free amino groups of aminoacyl residues in a peptide, thus marking those residues; the combined forms are known as DNP-proteins, Dnp-aminoacyl, etc., the fluorine having been replaced to leave a dinitrophenyl residue (DNP, Dnp, or N2Ph—) attached to the NH2 group. Hence, the N-terminal amino acid and lysine side chains will be covalently modified. SYN: Sanger reagent.

Medical dictionary. 2011.

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  • 1-fluoro-2,4-dinitrobenzene — 1 fluor 2,4 dinitrobenzenas statusas T sritis chemija formulė FC₆H₃(NO₂)₂ atitikmenys: angl. 1 fluoro 2,4 dinitrobenzene rus. 2,4 динитро 1 фторбензол …   Chemijos terminų aiškinamasis žodynas

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  • Sanger's reagent — Sanger s reagent, or 1 fluoro 2,4 dinitrobenzene (commonly called dinitrofluorobenzene or DNFB), is a chemical used for polypeptide sequencing. In 1945, Frederick Sanger described its use for determining the N terminal amino acid in polypeptide… …   Wikipedia

  • Reagent — A substance used to produce a chemical reaction to detect, measure, produce, etc. other substances. * * * Any substance added to a solution of another substance to participate in a chemical reaction. [Mod. L. reagens] amino acid r. a r. used in… …   Medical dictionary

  • FDNB — Abbreviation for fluoro 2,4 dinitrobenzene. * * * fluorodinitrobenzene …   Medical dictionary

  • 1-fluor-2,4-dinitrobenzenas — statusas T sritis chemija formulė FC₆H₃(NO₂)₂ atitikmenys: angl. 1 fluoro 2,4 dinitrobenzene rus. 2,4 динитро 1 фторбензол …   Chemijos terminų aiškinamasis žodynas

  • 2,4-динитро-1-фторбензол — 1 fluor 2,4 dinitrobenzenas statusas T sritis chemija formulė FC₆H₃(NO₂)₂ atitikmenys: angl. 1 fluoro 2,4 dinitrobenzene rus. 2,4 динитро 1 фторбензол …   Chemijos terminų aiškinamasis žodynas

  • organohalogen compound — Introduction  any of a class of organic compounds (organic compound) that contain at least one halogen (halogen element) ( fluorine [F], chlorine [Cl], bromine [Br], or iodine [I]) bonded to carbon. They are subdivided into alkyl, vinylic, aryl,… …   Universalium

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