fibronectins

fibronectins
High molecular weight multifunctional glycoproteins found on cell surface membranes and in blood plasma and other body fluids. F. are thought to function as adhesive ligandlike molecules that play a role in contact inhibition; also known as large external transformation sensitive protein (LETS), which is reduced after cells become transformed. SYN: zetaprotein. [L. fibra, fiber, + nexus, interconnection]
- plasma fibronectin a circulating α2-glycoprotein that functions as an opsonin, mediating reticuloendothelial and macrophage clearance of fibrin microaggregates, collagen debris, and bacterial particulates, protecting microvascular perfusion and lymphatic drainage.

Medical dictionary. 2011.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Extracellular matrix — Illustration depicting extracellular matrix (basement membrane and interstitial matrix) in relation to epithelium, endothelium and connective tissue Latin …   Wikipedia

  • Fibronectin — 1 PDB rendering based on 1e88 …   Wikipedia

  • Fibronectin type II domain — Pfam box Symbol = fn2 Name = width =250 caption =Collagen binding type II domain of seminal plasma protein PDC 109 Pfam= PF00040 InterPro= IPR000562 SMART= PROSITE = PDOC00022 SCOP = 1pdc TCDB = OPM family= 123 OPM protein= 1h8p… …   Wikipedia

  • CTSD — Cathepsin D, also known as CTSD, is a human gene.cite web | title = Entrez Gene: CTSD cathepsin D| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=1509| accessdate = ] PBB Summary section title = summary… …   Wikipedia

  • fibronectin — Glycoprotein of high molecular weight (2 chains each of 250 kD linked by disulphide bonds) that occurs in insoluble fibrillar form in extracellular matrix of animal tissues, and soluble in plasma, the latter previously known as cold insoluble… …   Dictionary of molecular biology

  • LETS — Acronym for large, external transformation sensitive fibronectin. See fibronectins. * * * large external transformation sensitive [protein]; Leiden Thrombophilia Study …   Medical dictionary

  • zetaprotein — SYN: fibronectins …   Medical dictionary

  • fibronectin — fi·bro·nec·tin .fī brə nek tən n any of a group of glycoproteins of cell surfaces, blood plasma, and connective tissue that promote cellular adhesion and migration * * * n. a large glycoprotein that acts as a host defence mechanism. In the plasma …   Medical dictionary

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”