fibronectins

fibronectins
High molecular weight multifunctional glycoproteins found on cell surface membranes and in blood plasma and other body fluids. F. are thought to function as adhesive ligandlike molecules that play a role in contact inhibition; also known as large external transformation sensitive protein (LETS), which is reduced after cells become transformed. SYN: zetaprotein. [L. fibra, fiber, + nexus, interconnection]
- plasma fibronectin a circulating α2-glycoprotein that functions as an opsonin, mediating reticuloendothelial and macrophage clearance of fibrin microaggregates, collagen debris, and bacterial particulates, protecting microvascular perfusion and lymphatic drainage.

Medical dictionary. 2011.

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