fibronectin

fibronectin
fi·bro·nec·tin .fī-brə-'nek-tən n any of a group of glycoproteins of cell surfaces, blood plasma, and connective tissue that promote cellular adhesion and migration

* * *

n.
a large glycoprotein that acts as a host defence mechanism. In the plasma it induces phagocytosis and on the cell surface it induces protein linkage which is important in the formation of new epithelium in wound healing. It is also involved in platelet aggregation. It is concentrated in connective tissue and the endothelium of the capillaries and is a component of the extracellular matrix.

* * *

fi·bro·nec·tin (fi″bro-nekґtin) [fibro- + nexus] any of several related adhesive glycoproteins. One form circulates in plasma, acting as an opsonin; another is a cell-surface protein that mediates cellular adhesive interactions. Fibronectins are important in connective tissue, where they cross-link to collagen, and are also involved in aggregation of platelets.

Medical dictionary. 2011.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Fibronectin — 1 PDB rendering based on 1e88 …   Wikipedia

  • fibronectin — fibronectin. См. фибронектин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • fibronectin — [fī΄brō nek′tin] n. an adhesive glycoprotein that helps destroy bacteria, etc. in the blood or that helps structure connective tissue …   English World dictionary

  • fibronectin — Glycoprotein of high molecular weight (2 chains each of 250 kD linked by disulphide bonds) that occurs in insoluble fibrillar form in extracellular matrix of animal tissues, and soluble in plasma, the latter previously known as cold insoluble… …   Dictionary of molecular biology

  • Fibronectin — Fibronektin (von lateinisch: fibra für „Faser“; nexus für „Verknüpfung“) ist ein extrazelluläres Glykoprotein, das in vielen physiologischen Abläufen, unter anderen in der Gewebsreparatur, der Embryogenese, der Hämostase sowie in der Migration… …   Deutsch Wikipedia

  • Fibronectin binding protein A — (FnbpA) is a S.aureus MSCRAMM cell surface bound protein that binds to both fibronectin and fibrinogen. It is an important virulence factor in S.aureus endocarditis …   Wikipedia

  • Fibronectin type II domain — Pfam box Symbol = fn2 Name = width =250 caption =Collagen binding type II domain of seminal plasma protein PDC 109 Pfam= PF00040 InterPro= IPR000562 SMART= PROSITE = PDOC00022 SCOP = 1pdc TCDB = OPM family= 123 OPM protein= 1h8p… …   Wikipedia

  • fibronectin — noun Etymology: fibr + Latin nectere to tie, bind + English in Date: 1976 any of a group of glycoproteins of cell surfaces, blood plasma, and connective tissue that promote cellular adhesion and migration …   New Collegiate Dictionary

  • fibronectin — /fuy breuh nek tin/, n. Cell Biol. a fibrous protein that binds to collagen, fibrin, and other proteins and also to the cell membranes, functioning as an anchor and connector. [1975 80; FIBRO + L nect(ere) to bind, join together (see CONNECT,… …   Universalium

  • fibronectin — noun An adhesive blood glycoprotein that has several cellular functions …   Wiktionary

  • Fibronectin — Fi|b|ro|nec|tin [lat. fibra = Faser u. nectere = verknüpfen; ↑ in (3)] das; s, e; veraltetes Syn.: Opsonin: in tierischen Organismen weit verbreitete faserige dimere Glykoproteine vom MG 500 000, die an zellulären Haftprozessen maßgeblich… …   Universal-Lexikon

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”