Natural product that inhibits topoisomerase II. SEE ALSO: etoposide. [epi- + Podophyllum, genus name of botanical source, + toxin]

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epi·podo·phyl·lo·tox·in (ep″ĭ-pod″o-filґo-tok″sin) [epi- + podophyllotoxin] a chemical derivative of podophyllotoxin from which the antineoplastic drugs etoposide and teniposide are derived.

Medical dictionary. 2011.

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  • Epipodophyllotoxin — Epipodophyllotoxins are alkaloids naturally occurring in the root of American Mayapple plant ( Podophyllum peltatum ).Some epipodophyllotoxin derivatives are currently used in the treatment of cancer. These include etoposide and teniposide. They… …   Wikipedia

  • epipodophyllotoxin — A substance being studied in the treatment of some types of cancer. Epipodophyllotoxin is extracted from the mandrake root Podophyllum peltatum. It is a type of topoisomerase inhibitor …   English dictionary of cancer terms

  • List of oncology-related terms — This is a list of terms related to oncology. The original source for this list was the U.S. National Cancer Institute s public domain Dictionary of Cancer Terms . NOTOC 1 * 10 propargyl 10 deazaaminopterin * 12 O tetradecanoylphorbol 13 acetate * …   Wikipedia

  • History of cancer chemotherapy — The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs. Cancer drug development has exploded since then into a multi billion dollar industry. The targeted therapy revolution has… …   Wikipedia

  • Etoposide — drugbox IUPAC name = 4 demethyl epipodophyllotoxin 9 [4,6 O ( R ) ethylidene beta D glucopyranoside] , 4 (dihydrogen phosphate) CAS number = 33419 42 0 ATC prefix = L01 ATC suffix = CB01 ATC supplemental = PubChem = 36462 DrugBank = APRD00239 C …   Wikipedia

  • VP-16 — abbr. med. epipodophyllotoxin – эпидофиллотоксин …   Dictionary of English abbreviation

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