dicumarol

dicumarol
An anticoagulant that inhibits the formation of prothrombin in the liver. Acts as an antagonist of vitamin K; discovered as the causative agent in spoiled hay, which produced bleeding in cattle (sweet clover disease). SYN: bishydroxycoumarin.

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di·cu·ma·rol also di·cou·ma·rol dī-'k(y)ü-mə-.rȯl, -.rōl n a crystalline compound C19H12O6 that acts similarly to warfarin and is used esp. in preventing and treating thromboembolic disease

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di·cu·ma·rol (di-kooґmə-rol) 1. a coumarin anticoagulant found in spoiled sweet clover; animals eating the clover may develop the hemorrhagic condition known as sweet clover disease. 2. a synthetic preparation of the same substance, used as an oral anticoagulant; it acts by inhibiting the hepatic synthesis of vitamin K–dependent coagulation factors (prothrombin and factors VII, IX, and X) and proteins C and S.

Medical dictionary. 2011.

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  • Dicumarol — Saltar a navegación, búsqueda Dicumarol Aviso …   Wikipedia Español

  • dicumarol — m. farm. Molécula de estructura similar a la vitamina K que actúa como anticoagulante. Se utiliza en las trombosis y embolias postoperatorias y como tratamiento curativo en las trombosis arteriales y venosas. Medical Dictionary. 2011. dicu …   Diccionario médico

  • Dicumarol —   [Kurzwort] das, s, weiße, bitterlich schmeckende kristalline Substanz, Abkömmling des Cumarins, ein als Gegenspieler des Vitamins K wirkendes blutgerinnungshemmendes Mittel; wird u. a. zur Behandlung von Thrombosen verwendet, ferner als Gift in …   Universal-Lexikon

  • dicumarol — ☆ dicumarol [dī ko͞o′mə rôl΄, dī ko͞o′mərōl΄; dīkyo͞o′mə rôl΄ ] n. [< dicoumarin, earlier name for this substance ( DI 1 + (bishydroxy)coumarin) + OL1] a white, crystalline powder, C19H12O6, originally extracted from spoiled sweet clover, used …   English World dictionary

  • Dicumarol — Strukturformel Allgemeines Freiname Dicumarol Andere Namen …   Deutsch Wikipedia

  • dicumarol — noun an anticoagulant drug that has now been largely replaced by warfarin • Syn: ↑dicoumarol • Hypernyms: ↑anticoagulant, ↑anticoagulant medication, ↑decoagulant * * * /duy kooh meuh rawl , rol , kyooh /, Pharm. a synthetic coumarin derivative,… …   Useful english dictionary

  • dicumarol — also dicoumarol noun Etymology: di + coumarin + 1 ol Date: 1942 a crystalline compound C19H12O6 originally obtained from spoiled sweet clover hay and used to delay clotting of blood especially in preventing and treating thromboembolic dis …   New Collegiate Dictionary

  • dicumarol — /duy kooh meuh rawl , rol , kyooh /, Pharm. a synthetic coumarin derivative, C19H12O6, used chiefly to prevent blood coagulation and in the treatment of arterial thrombosis. Also, dicoumarin, dicoumarol. [resp. of DI 1 + COUMAR(IN) + OL] * * * …   Universalium

  • dicumarol — di•cu•ma•rol or dicoumarol [[t]daɪˈku məˈrɔl, ˌrɒl, ˈkyu [/t]] n. pha a synthetic coumarin derivative, C19H12O6, used chiefly to prevent blood clots • Etymology: resp. of di I+coumar(in)+ ol I …   From formal English to slang

  • Dicoumarol — Not to be confused with coumadin or coumarin. Dicoumarol Systematic (IUPAC) name 3,3 methylenebis(4 hydroxy 2H chromen 2 one) Cl …   Wikipedia

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