An antibiotic used in the treatment of leprosy and certain cutaneous diseases such as dermatitis herpetiformis, is active against the tubercle bacillus, is used in the treatment of bovine coccidiosis and streptococcal mastitis, and is used as a second-line agent in Pneumocystis carinii pneumonia, a disease common in AIDS patients.

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dap·sone 'dap-.sōn, -.zōn n an antimicrobial agent C12H12N2O2S used esp. to treat leprosy and dermatitis herpetiformis called also diaminodiphenyl sulfone

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a drug (see sulphone) used to treat leprosy and dermatitis herpetiformis. It is administered by mouth or injection; the most common side-effects are allergic skin reactions.

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dap·sone (DDS) (dapґsōn) [USP] an antibacterial and antifungal, the parent compound of a group of sulfonamide-like sulfones, including acedapsone, acetosulfone sodium, glucosulfone sodium, sulfoxone sodium, and solapsone. Dapsone and its derivatives are bacteriostatic for a broad spectrum of gram-negative and gram-positive organisms, including Mycobacterium tuberculosis and M. leprae, and have suppressive action on Plasmodium falciparum. Dapsone is administered orally as a leprostatic, especially in tuberculoid and lepromatous leprosy, as a dermatitis herpetiformis suppressant; in the prophylaxis of falciparum malaria; and for the prophylaxis and treatment of pneumocystis pneumonia. Called also diaminodiphenylsulfone or DDS.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Dapsone — Systematic (IUPAC) name 4 [(4 aminobenzene)sulfonyl]aniline …   Wikipedia

  • Dapsone — Général Nom IUPAC 4,4 sulfonyldianiline No CAS …   Wikipédia en Français

  • dapsone — [dap′sōn΄] n. a white, crystalline powder, (C6H4NH2) 2SO2, used in the treatment of leprosy and of a dermatitis somewhat resembling herpes …   English World dictionary

  • dapsone — noun Etymology: diamine + phenyl + sulfone Date: 1952 an antimicrobial agent C12H12N2O2S used especially to treat leprosy and a chronic form of dermatitis …   New Collegiate Dictionary

  • dapsone — Drug related to the sulphonamides (diaminodiphenyl sulphone) that is used to treat leprosy (causative agent is Mycobacterium leprae ). May act by inhibiting folate synthesis …   Dictionary of molecular biology

  • dapsone — /dap sohn/, n. Pharm. an antibacterial substance, C12H12N2O2S, used to treat leprosy and certain forms of dermatitis. Also called DDS [1965 70; d(i)a(minodi)p(henyl) sulfone] * * * …   Universalium

  • dapsone — noun A drug, 4 [(4 aminobenzene)sulfonyl]aniline, used in the treatment of leprosy and similar infections …   Wiktionary

  • dapsone — n. antibiotic used to treat leprosy and certain types of skin diseases …   English contemporary dictionary

  • dapsone — [ dapsəʊn] noun Medicine a sulphur containing drug used to treat leprosy. Origin 1950s: from elements of the systematic name dipara aminophenyl sulphone …   English new terms dictionary

  • dapsone — dap·sone …   English syllables

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