1. A general descriptive term applied to anticoagulants and other drugs derived from dicumarol, a component of the Tonka bean. 2. A fragrant neutral principle obtained from the Tonka bean, Dypterix odorata, and made synthetically from salicylic aldehyde; it is used to disguise unpleasant odors. SYN: coumaric anhydride, cumarin. [coumarou, native name of Tonka bean]

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cou·ma·rin 'kü-mə-rən n a toxic white crystalline lactone C9H6O2 with an odor of new-mown hay found in plants or made synthetically and used esp. in perfumery and as the parent compound in various anticoagulant agents (as warfarin) also a derivative of this compound

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cou·ma·rin (kooґmə-rin) 1. a principle with a bitter taste and an odor like that of vanilla beans, derived from tonka bean, sweet clover, and other plants, and also prepared synthetically. It contains a factor, dicumarol, that inhibits the hepatic synthesis of the vitamin K–dependent coagulation factors (prothrombin, factors VII, IX, and X), and a number of its derivatives are used widely as anticoagulants in the treatment of disorders in which there is excessive or undesirable clotting, such as thrombophlebitis, pulmonary embolism, and certain cardiac conditions. 2. any derivative of coumarin or any synthetic compound with coumarin-like actions.

Medical dictionary. 2011.

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  • Coumarin — Cou ma*rin (k[=oo] m[.a]*r[i^]n), n. [F., fr. coumarou, a tree of Guiana.] (Chem.) The concrete essence of the tonka bean, the fruit of {Dipterix (formerly Coumarouna) odorata} and consisting essentially of coumarin proper, which is a white… …   The Collaborative International Dictionary of English

  • Coumarin — (Chem.), so v.w. Cumarin …   Pierer's Universal-Lexikon

  • coumarin — [ko͞o′mə rin΄] n. [Fr coumarine < coumarou, tonka bean < Port < Tupí cumaru] a toxic, white crystalline substance, C9H6O2, with the odor of vanilla, obtained from the tonka bean and certain plants or made synthetically: used in perfumes …   English World dictionary

  • Coumarin — Not to be confused with coumadin or dicoumarol. This article is about the sweet smelling plant substance called coumarin. For the anticoagulant rodenticide poisons often called coumarins or coumadins , see 4 hydroxycoumarins. Coumarin …   Wikipedia

  • Coumarin — Strukturformel Allgemeines Name Cumarin Andere Namen 1,2 Benzopyron 2H 1 Benzopyran 2 on o Cumarsäurelacton Ton …   Deutsch Wikipedia

  • coumarin — (= O hydroxycinnamic acid) Pleasant smelling compound found in many plants and released on wilting (probably a major component of the smell of fresh hay). Has anticoagulant activity by competing with Vitamin K. Coumarin derivatives have anti… …   Dictionary of molecular biology

  • coumarin — /kooh meuh rin/, n. a fragrant crystalline substance, C9H6O2, obtained from the tonka bean, sweet clover, and certain other plants or prepared synthetically, used chiefly in soaps and perfumery. Also, cumarin. [1820 30; < F coumarine, equiv. to… …   Universalium

  • coumarin — kumarinas statusas T sritis chemija formulė OC₉H₆(=O) atitikmenys: angl. coumarin rus. кумарин ryšiai: sinonimas – 1 benzpiran 2 onas …   Chemijos terminų aiškinamasis žodynas

  • coumarin — noun Etymology: French coumarine, from coumarou tonka bean tree, from Spanish or Portuguese; Spanish cumarú, from Portuguese, from Tupi *kumarú, *kumbarú Date: 1830 a toxic white crystalline lactone C9H6O2 with an odor of new mown hay found in… …   New Collegiate Dictionary

  • coumarin — noun the bicyclic aromatic compound 1,2 benzopyrone or any of its derivatives …   Wiktionary

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